We tested the hypothesis that vitamin D supplementation is associated with early body mass index (BMI) patterns.Using retrospective longitudinal data of infants and toddlers in a 2-year follow-up study, we identified BMI-for-age Z score (BAZ) growth trajectories using latent class growth modeling (LCGM) analysis. Logistic regression models were adopted to investigate the impact of vitamin D supplementation on BAZ patterns.Five BAZ trajectories were derived using LCGM. Higher intake of vitamin D supplement was significantly associated with lower odds of rapid weight gain or mild undernutrition in the first 2 years (odds ratios: 0.60-0.83 for class 2: early rapid growth; 0.69-0.82 for class 3: early weight loss, late rapid growth; 0.83-0.89 for class 4: suboptimal growth). Adherence to 400 IU Vitamin D ≥ 1 year was significantly associated with less likelihood of being in class 3 (odds ratio 0.17).Among infants and toddlers aged 0 to 2 years, dietary supplementation of vitamin D is insufficient in rural areas of China. Insufficient vitamin D intake was found to be associated with suboptimal BAZ growth at early stages. Effective collaboration is needed between pediatricians and caregivers, to assure adherence to the nutritional guideline.
基金：
This study was supported by the Shanghai
Municipal Committee of Science and Technology
(grant numbers: 16411970100, 18411967700);
Shanghai Children’s Health Services Capacity
Planning Special Program for Advanced
Pediatric Overseas Research Team Training
Program (grant number: GDEK201710); and
Shanghai Municipal Health Commission (grant
number: GWV-10.1-XK19).
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2020]版：
大类|4 区医学
小类|4 区医学：研究与实验4 区药学
最新[2023]版：
大类|4 区医学
小类|4 区医学：研究与实验4 区药学
第一作者：
第一作者机构：[1]Department of Child Health Care, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China.
共同第一作者：
通讯作者：
通讯机构：[1]Department of Child Health Care, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China.[*1]Department of Child Health Care, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Luding Road 355, Putuo District 200062, Shanghai, China.
推荐引用方式(GB/T 7714)：
Zheng Xiaofei,Wu Qijun,Weng Dadong,et al.Adherence to supplemental vitamin D intake and infant weight gain: a retrospective cohort study in rural southwestern China[J].The Journal of international medical research.2020,48(11):300060520969311.doi:10.1177/0300060520969311.
APA：
Zheng Xiaofei,Wu Qijun,Weng Dadong,Fu Yeju,Yue Duxian&Wang Yu.(2020).Adherence to supplemental vitamin D intake and infant weight gain: a retrospective cohort study in rural southwestern China.The Journal of international medical research,48,(11)
MLA：
Zheng Xiaofei,et al."Adherence to supplemental vitamin D intake and infant weight gain: a retrospective cohort study in rural southwestern China".The Journal of international medical research 48..11(2020):300060520969311
