机构:[1]The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.[2]Yunnan Provincial Center for Disease Control and Prevention, 158 Dongsi street, Kunming, Yunnan 650022, People’s Republic of China.[3]Wenshan Prefecture Center for Disease Control and Prevention, Wenshan, Yunnan, China
The emergence of human infection with avian influenza A(H7N9) virus was reported in Wenshan City, southwestern China in 2017. The study describes the epidemiological and virological features of the outbreak and discusses the origin of the infection.Poultry exposure and timelines of key events for each patient were collected. Samples derived from the patients, their close contacts, and environments were tested for influenza A(H7N9) virus by real-time reverse transcription polymerase chain reaction. Genetic sequencing and phylogenetic analysis were also conducted.Five patients were reported in the outbreak. An epidemiological investigation showed that all patients had been exposed at live poultry markets. The A(H7N9) isolates from these patients had low pathogenicity in avian species. Both epidemiological investigations of chicken sources and phylogenetic analysis of viral gene sequences indicated that the source of infection was from Guangxi Province, which lies 100 km to the east of Wenshan City.In the study, a sudden emergence of human cases of H7N9 was documented in urban area of Wenshan City. Chickens were an important carrier in the H7N9 virus spreading from Guangxi to Wenshan. Hygienic management of live poultry markets and virological screening of chickens transported across regions should be reinforced to limit the spread of H7N9 virus.
基金:
This research received the grants from funding of the Yunnan Provincial
Foundation for Health Programmes (Grant no. [2019] 70) when performing
study design and data collection, and funding of Guizhou Construction
Platform for Talents Training ([2017]5735–31) when performing data analysis,
manuscript writing, and interpretation of data.
语种:
外文
PubmedID:
中科院(CAS)分区:
出版当年[2020]版:
大类|3 区医学
小类|4 区传染病学
最新[2023]版:
大类|3 区医学
小类|3 区传染病学
第一作者:
第一作者机构:[1]The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.
共同第一作者:
通讯作者:
推荐引用方式(GB/T 7714):
Jiang Li,Zhao Xiaonan,Xu Wen,et al.Emergence of human avian influenza A(H7N9) virus infections in Wenshan City in Southwest China, 2017[J].BMC infectious diseases.2020,20(1):154.doi:10.1186/s12879-020-4858-6.
APA:
Jiang Li,Zhao Xiaonan,Xu Wen,Zhou Xuehua,Luo Chunrui...&Li Duo.(2020).Emergence of human avian influenza A(H7N9) virus infections in Wenshan City in Southwest China, 2017.BMC infectious diseases,20,(1)
MLA:
Jiang Li,et al."Emergence of human avian influenza A(H7N9) virus infections in Wenshan City in Southwest China, 2017".BMC infectious diseases 20..1(2020):154