Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function
机构：[1]Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, KunmingInstitute of Zoology, Kunming, Yunnan, China[2]Department of Biomedicine and Centre for Integrative Sequencing (iSEQ), AarhusUniversity, 8000 Aarhus C, Denmark[3]The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus andCopenhagen, Denmark[4]Department of Genomics, Life & Brain Center, and Institute of Human Genetics, University of Bonn, Bonn,Germany[5]Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD[6]First Affiliated Hospital of GannanMedical University, Ganzhou, Jiangxi, China[7]Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health,Medical Faculty of Mannheim, University of Heidelberg, Mannheim, Germany[8]Research Department, Psychiatric Hospital, AarhusUniversity Hospital, Aarhus, Denmark[9]Center for Biomarker Research and Personalized Medicine, Virginia Commonwealth University[10]Centre for Psychiatric Research, Aarhus University Hospital, Risskov, Denmark[11]National Centre for Register-based Research, AarhusUniversity, Aarhus, Denmark[12]Department of Microbiology and Immunology, Medical University of South Carolina, Charleston,SC[13]Division of Medical Genetics, Department of Biomedicine, University Basel, Basel, Switzerland[14]Institute of Neuroscience andMedicine (INM-1), Research Center Juelich, Juelich, Germany[15]Department of Psychiatry and Psychotherapy, University Medical CenterGeorg-August-Universität, 37075 Goettingen, Germany[16]Institute of Psychiatric Phenomics and Genomics (IPPG), Ludwig-Maximilians-University Munich[17]State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy ofSciences, Kunming, Yunnan, China[18]Departments of Biomedical Informatics and Psychiatry, Vanderbilt University School of Medicine,Nashville, TN 37232, USA[19]Flaum Eye Institute and Department of Ophthalmology, University of Rochester, Rochester, NY 14642,USA[20]CAS Center for Excellence in Brain Science, Chinese Academy of Sciences, Shanghai, 200031, China
X.J.L was supported by the 100 Talents Program
(BaiRenJiHua) of the Chinese Academy of Sciences.
Y.G.Y was supported by the Strategic Priority
Research Program (B) of the Chinese Academy of
Sciences (XDB02020000). The research leading to
these results has received funding from the European
Community’s Seventh Framework Programme: FP7/
Health-2011-1.1-2 under grant agreement n°279227
and Health-F4-2009–242257 to M.R. (ADAMS project).
This study was also supported by the German
Federal Ministry of Education and Research (BMBF)
through the Integrated Genome Research Network
(IG) MooDS (Systematic Investigation of the
Molecular Causes of Major Mood Disorders and
Schizophrenia; grant 01GS08144 to M.M.N. and
S.C., grant 01GS08147 to M.R.), under the auspices
of the National Genome Research Network plus
(NGFNplus), and through the Integrated Network
IntegraMent (Integrated Understanding of Causes and
Mechanisms in Mental Disorders), under the auspices
of the e:Med Programme. M.M.N. is a member of the
DFG-funded Excellence-Cluster ImmunoSensation
and also received support from the Alfried Krupp von
Bohlen und Halbach-Stiftung. We thank the grant
support from National Institutes of Health grant
(R01LM011177).
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外文
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出版当年[2015]版：
大类|1 区医学
小类|1 区精神病学
最新[2023]版：
大类|1 区医学
小类|1 区精神病学
第一作者：
第一作者机构：[1]Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, KunmingInstitute of Zoology, Kunming, Yunnan, China[*1]Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China
共同第一作者：
通讯作者：
通讯机构：[1]Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, KunmingInstitute of Zoology, Kunming, Yunnan, China[*1]Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China
推荐引用方式(GB/T 7714)：
Xiong-Jian Luo,Manuel Mattheisen,Ming Li,et al.Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function[J].Schizophrenia bulletin.2015,41(6):1294-308.doi:10.1093/schbul/sbv017.
APA：
Xiong-Jian Luo,Manuel Mattheisen,Ming Li,Liang Huang,Marcella Rietschel...&Yong-Gang Yao.(2015).Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function.Schizophrenia bulletin,41,(6)
MLA：
Xiong-Jian Luo,et al."Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function".Schizophrenia bulletin 41..6(2015):1294-308
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