Tubridge flow diverter is a widely used device aimed at reconstructing parent artery and occluding complex aneurysm in China. The experience of Tubridge in treating unruptured vertebra-basilar artery dissecting aneurysms is still limited. In this study, we aimed to evaluate the safety and efficacy of Tubridge flow diverter for the treatment of vertebra-basilar artery dissecting aneurysms.We reviewed the clinical records of aneurysms treated with Tubridge flow diverter between 2019 and 2021 in a national cerebrovascular disease center. Therapeutic process, occlusion rate and clinical outcome were compared.Twenty-three patients with twenty-three vertebra-basilar artery aneurysms were identified. The results showed that the mean length and mean maximal width were 15.14/9.14 mm in the vertebra-basilar artery. Twenty-four Tubridge flow diverters were successfully implanted without unfold failure. Complete occlusion rate on the last angiographic follow-up was achieved in 78.26% of vertebra-basilar artery aneurysms. Fifteen branch arteries were covered, and only one branch artery disappeared at follow-up. Mild asymptomatic cerebral infarction occurred in three patients (13.04%), intracranial hemorrhage were non-encountered in the patients.Our preliminary experience suggests that the Tubridge flow diverter might be a safe and effective tool for dissecting cerebral aneurysms. Branch arteries were well protected and mild asymptomatic cerebral infarction occurred in some patients. Adequate evidences are required to clear the definite indications and complications in a multicenter randomized controlled trial with a long-term follow-up.Copyright © 2023. Published by Elsevier Inc.