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The relationship between maternal exposure to ambient air pollutants and premature rupture of membranes: A systematic review and meta-analysis

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机构: [1]Chinese Acad Med Sci, Beijing Hosp, Beijing Inst Geriatr, Inst Geriatr Med,Key Lab Geriatr,Natl Ctr Gerontol, Beijing 100730, Peoples R China [2]Chinese Acad Med Sci, Inst Geriatr Med, Dept Gynecol & Obstet, Beijing Hosp,Natl Ctr Gerontol, Beijing 100730, Peoples R China [3]Kunming Univ Sci & Technol, Peoples Hosp Yunnan Prov 1, Affiliated Hosp, Dept Obstet, Kunming 650500, Peoples R China [4]Chinese Acad Med Sci & Peking Union Med Coll, Beijing Hosp, Beijing 100730, Peoples R China [5]Maternal & Child Hlth Care Hosp Mentougou Dist, Beijing, Peoples R China
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关键词: Air pollution Premature rupture of membranes Pregnancy Particulate matter Reproductive health

摘要:
Air pollution is an environmental stimulus that may predispose pregnant women to preterm rapture of membrane (PROM). However, the relationship of maternal exposure to air pollutants and PROM is still unclear. To investigate the relationship between the long-term and short-term maternal exposure to air pollution and PROM. We searched all studies published in PubMed, Embase and Web of Science up to February 2024. The studies provided quantitative effect estimates with 95% confidence intervals, for the impact of short-term (<30 days) or long-term (>= 30 days) maternal exposure to air pollutants on PROM, preterm PROM (PPROM) or term PROM (TPROM). The odds ratio (OR), risk ratio (RR), or hazard ratio (HR), with 95% confidence intervals was extracted, and RR or HR were deemed as OR because of the low prevalence of PROM. Fixed- or random-effects meta-analyses performed. In total, 17 relevant studies were included. Maternal exposure to PM2.5 in the second trimester increases the risk of PROM (pooled OR = 1.15, 95%CI: 1.05-1.26). Maternal exposure to PM10, NO2, NO, CO and SO2 during pregnancy and short-term maternal exposure to PM2.5, NO2, SO2 and O-3 also associate with PROM occurrence. The results of the study show that both long-term maternal exposure in the second or third trimester and short-term maternal exposure to ambient air pollution can increase the risk of PROM.

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出版当年[2025]版:
大类 | 2 区 环境科学与生态学
小类 | 2 区 环境科学
最新[2025]版:
大类 | 2 区 环境科学与生态学
小类 | 2 区 环境科学
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出版当年[2023]版:
Q1 ENVIRONMENTAL SCIENCES
最新[2024]版:
Q1 ENVIRONMENTAL SCIENCES

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第一作者机构: [1]Chinese Acad Med Sci, Beijing Hosp, Beijing Inst Geriatr, Inst Geriatr Med,Key Lab Geriatr,Natl Ctr Gerontol, Beijing 100730, Peoples R China
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通讯机构: [1]Chinese Acad Med Sci, Beijing Hosp, Beijing Inst Geriatr, Inst Geriatr Med,Key Lab Geriatr,Natl Ctr Gerontol, Beijing 100730, Peoples R China [2]Chinese Acad Med Sci, Inst Geriatr Med, Dept Gynecol & Obstet, Beijing Hosp,Natl Ctr Gerontol, Beijing 100730, Peoples R China [3]Kunming Univ Sci & Technol, Peoples Hosp Yunnan Prov 1, Affiliated Hosp, Dept Obstet, Kunming 650500, Peoples R China [*1]Department of Gynecology and Obstetrics, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China
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