Air pollution is an environmental stimulus that may predispose pregnant women to preterm rapture of membrane (PROM). However, the relationship of maternal exposure to air pollutants and PROM is still unclear. To investigate the relationship between the long-term and short-term maternal exposure to air pollution and PROM. We searched all studies published in PubMed, Embase and Web of Science up to February 2024. The studies provided quantitative effect estimates with 95% confidence intervals, for the impact of short-term (<30 days) or long-term (>= 30 days) maternal exposure to air pollutants on PROM, preterm PROM (PPROM) or term PROM (TPROM). The odds ratio (OR), risk ratio (RR), or hazard ratio (HR), with 95% confidence intervals was extracted, and RR or HR were deemed as OR because of the low prevalence of PROM. Fixed- or random-effects meta-analyses performed. In total, 17 relevant studies were included. Maternal exposure to PM2.5 in the second trimester increases the risk of PROM (pooled OR = 1.15, 95%CI: 1.05-1.26). Maternal exposure to PM10, NO2, NO, CO and SO2 during pregnancy and short-term maternal exposure to PM2.5, NO2, SO2 and O-3 also associate with PROM occurrence. The results of the study show that both long-term maternal exposure in the second or third trimester and short-term maternal exposure to ambient air pollution can increase the risk of PROM.
基金:
This study was funded by National High Level Hospital Clinical
Research Funding (BJ-2018-204 and BJ-2023-112), National Natural
Science Foundation of China (No. 81302277), Yunnan Provincial Science and Technology Department-2020 Kunming Medical University
Joint Special Project on Applied Basic Research (202001AY070001-128)
第一作者机构:[1]Chinese Acad Med Sci, Beijing Hosp, Beijing Inst Geriatr, Inst Geriatr Med,Key Lab Geriatr,Natl Ctr Gerontol, Beijing 100730, Peoples R China
通讯作者:
通讯机构:[1]Chinese Acad Med Sci, Beijing Hosp, Beijing Inst Geriatr, Inst Geriatr Med,Key Lab Geriatr,Natl Ctr Gerontol, Beijing 100730, Peoples R China[2]Chinese Acad Med Sci, Inst Geriatr Med, Dept Gynecol & Obstet, Beijing Hosp,Natl Ctr Gerontol, Beijing 100730, Peoples R China[3]Kunming Univ Sci & Technol, Peoples Hosp Yunnan Prov 1, Affiliated Hosp, Dept Obstet, Kunming 650500, Peoples R China[*1]Department of Gynecology and Obstetrics, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China
推荐引用方式(GB/T 7714):
Liang Yaxin,Li Min,Lyu Qiubo,et al.The relationship between maternal exposure to ambient air pollutants and premature rupture of membranes: A systematic review and meta-analysis[J].ENVIRONMENTAL POLLUTION.2024,347:doi:10.1016/j.envpol.2024.123611.
APA:
Liang, Yaxin,Li, Min,Lyu, Qiubo,Li, Pingping,Lyu, Yuhan...&Peng, Wuqiang.(2024).The relationship between maternal exposure to ambient air pollutants and premature rupture of membranes: A systematic review and meta-analysis.ENVIRONMENTAL POLLUTION,347,
MLA:
Liang, Yaxin,et al."The relationship between maternal exposure to ambient air pollutants and premature rupture of membranes: A systematic review and meta-analysis".ENVIRONMENTAL POLLUTION 347.(2024)