A commentary on "SIRT1-Rab7 axis attenuates NLRP3 and STING activation through late endosomal-dependent mitophagy during sepsis-induced acute lung injury"
机构：[1]Department of Emergency, Maitreya Traditional Chinese Medicine Hospital, Yunnan, China.[2]Department of Pediatrics, Maitreya Traditional Chinese Medicine Hospital, Yunnan, China.[3]Emergency and Critical Care Center, Southern Central Hospital of Yunnan Province (The First People's Hospital of Honghe State), Yunnan, China.
Dear editor,
With high rates of morbidity and death of up to 30%, sepsis is a major public health concern that endangers the lives of patients in intensive care units (ICUs) as well as ordinary hospital wards[1-2]. Sepsis is a
life-threatening organ failure brought on by an uncontrolled host immunological reaction to an infection.Essentially, this dysregulated immune response damages several organs by aggravating the systemic inflammatory
response and failing to defend the body against infection. The lungs are frequently the first and most vulnerable
organs to invade among those impacted by multi-organ failure in sepsis. According to research, acute lung injury (ALI) will occur in 25% to 50% of sepsis patients.
基金：
High-level TCM talent training in Yunnan Province (2024); Scientific Research Project of Qingdao University Medical Group (YLJT20222013); Department of Science and Technology of Yunnan Province-Joint Special Fund for Applied Basic Research of Kunming Medical University (202301AY070001-040)
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外文
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无
最新[2025]版：
大类|2 区医学
小类|2 区外科
第一作者：
第一作者机构：[1]Department of Emergency, Maitreya Traditional Chinese Medicine Hospital, Yunnan, China.
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Zhao Chang'An,Li Yani,Fu Shibiao,et al.A commentary on "SIRT1-Rab7 axis attenuates NLRP3 and STING activation through late endosomal-dependent mitophagy during sepsis-induced acute lung injury"[J].International Journal Of Surgery (London, England).2025,doi:10.1097/JS9.0000000000002509.
APA：
Zhao Chang'An,Li Yani,Fu Shibiao&Shen Lan.(2025).A commentary on "SIRT1-Rab7 axis attenuates NLRP3 and STING activation through late endosomal-dependent mitophagy during sepsis-induced acute lung injury".International Journal Of Surgery (London, England),,
MLA：
Zhao Chang'An,et al."A commentary on "SIRT1-Rab7 axis attenuates NLRP3 and STING activation through late endosomal-dependent mitophagy during sepsis-induced acute lung injury"".International Journal Of Surgery (London, England) .(2025)
