机构：[1]The National Clinical Research Center for Mental Disorders, China & Center of Depression, Beijing Institute for BrainDisorders & Mood Disorders Center, Beijing Anding Hospital, Capital Medical University, Beijing, China[2]Unit ofPsychiatry, Faculty of Health Sciences, University of Macau, Macao SAR, China[3]Peking University Institute of MentalHealth (the sixth Hospital) & National Clinical Research Center for Mental Disorders & the key Laboratory of MentalHealth, Ministry of Health (Peking University), Beijing, China[4]Division of Mood Disorders, Shanghai Mental HealthCenter, Shanghai Jiao Tong University School of Medicine, Shanghai, China[5]The University of Notre Dame Australia/Marian Centre, Perth, Australia[6]School of Psychiatry & Clinical Neurosciences, University of Western Australia,Perth, Australia[7]Department of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia[8]Departmentof Psychiatry, Chinese University of Hong Kong, Hong Kong SAR, China[9]The Second Affiliated Hospital, Collegeof Medicine, Zhejiang University, Hangzhou, Zhejiang province, China[10]Division of Mood Disorders, ShenzhenMental Health Centre, Shenzhen, Guangdong province, China深圳市康宁医院深圳医学信息中心[11]Department of Psychiatry, Xijing Hospital, FourthMilitary Medical University, Xi’an, Shannxi province, China[12]Department of Psychiatry, the First Affiliated Hospitalof Kunming Medical University, Kunming, Yunnan province, China昆明医科大学附属第一医院
Little is known about the demographic and clinical differences between short and long duration of untreated bipolar disorder (DUB) in Chinese patients. This study examined the demographic and clinical features of short (<= 2 years) and long DUB (> 2 years) in China. A consecutively recruited sample of 555 patients with bipolar disorder (BD) was examined in 7 psychiatric hospitals and general hospital psychiatric units across China. Patients' demographic and clinical characteristics were collected using a standardized protocol and data collection procedure. The mean DUB was 3.2 +/- 6.0 years; long DUB accounted for 31.0% of the sample. Multivariate analyses revealed that longer duration of illness, diagnosis of BD type II, and earlier misdiagnosis of BD for major depressive disorder or schizophrenia were independently associated with long DUB. The mean DUB in Chinese BD patients was shorter than the reported figures from Western countries. The long-term impact of DUB on the outcome of BD is warranted.
基金：
Capital City Clinical Practice and Research Funding of Beijing Municipal Science & Technology Commission [Z141107002514033]; Clinical Medicine Development Funding of Beijing Municipal Administration of Hospitals [ZYLX201403, ZYLX201607]
第一作者机构：[1]The National Clinical Research Center for Mental Disorders, China & Center of Depression, Beijing Institute for BrainDisorders & Mood Disorders Center, Beijing Anding Hospital, Capital Medical University, Beijing, China[2]Unit ofPsychiatry, Faculty of Health Sciences, University of Macau, Macao SAR, China
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Ling Zhang,Xin Yu,Yi-Ru Fang,et al.Duration of untreated bipolar disorder: a multicenter study[J].SCIENTIFIC REPORTS.2017,7:doi:10.1038/srep44811.
APA：
Ling Zhang,Xin Yu,Yi-Ru Fang,Gabor S. Ungvari,Chee H. Ng...&Yu-Tao Xiang.(2017).Duration of untreated bipolar disorder: a multicenter study.SCIENTIFIC REPORTS,7,
MLA：
Ling Zhang,et al."Duration of untreated bipolar disorder: a multicenter study".SCIENTIFIC REPORTS 7.(2017)
