Overview of the improvement of the ring-stage survival assay - a novel phenotypic assay for the detection of artemisinin-resistant Plasmodium falciparum
机构：[1]Department of Pathogen Biology and Immunology, Kunming Medical University, Kunming Yunnan 650500, China[2]Biomedical Engineering Research Center, Kunming Medical University, Kunming Yunnan 650500, China[3]Guangxi Zhuang Autonomous Region People’s Hospital, Nanning Guangxi 530021, China[4]Transfusion Medicine Research Department, Yunnan Kunming Blood Center, Kunming Yunnan 650500, China[5]Department of Infectious Diseases, The First Affiliated Hospital, Kunming Medical University, Kunming Yunnan 650032, China昆明医科大学附属第一医院
Artemisinin resistance in Plasmodium falciparum threatens the remarkable efficacy of artemisinin-based combination therapies worldwide. Thus, greater insight into the resistance mechanism using monitoring tools is essential. The ring-stage survival assay is used for phenotyping artemisinin-resistance or decreased artemisinin sensitivity. Here, we review the progress of this measurement assay and explore its limitations and potential applications.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [31260508, U1202226]; Yunnan province
第一作者机构：[1]Department of Pathogen Biology and Immunology, Kunming Medical University, Kunming Yunnan 650500, China
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Zhang Jie,Feng Guo-Hua,Zou Chun-Yan,et al.Overview of the improvement of the ring-stage survival assay - a novel phenotypic assay for the detection of artemisinin-resistant Plasmodium falciparum[J].ZOOLOGICAL RESEARCH.2017,38(6):317-320.doi:10.24272/j.issn.2095-8137.2017.075.
APA：
Zhang, Jie,Feng, Guo-Hua,Zou, Chun-Yan,Su, Pin-Can,Liu, Huai-E&Yang, Zhao-Qing.(2017).Overview of the improvement of the ring-stage survival assay - a novel phenotypic assay for the detection of artemisinin-resistant Plasmodium falciparum.ZOOLOGICAL RESEARCH,38,(6)
MLA：
Zhang, Jie,et al."Overview of the improvement of the ring-stage survival assay - a novel phenotypic assay for the detection of artemisinin-resistant Plasmodium falciparum".ZOOLOGICAL RESEARCH 38..6(2017):317-320
生物学