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Research progress on the regulation of tumor initiation and development by the forkhead box Q1 gene(Open Access)

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收录情况： ◇ SCIE

作者：
Tang, H[1,2] * ; Zhang, J[1] ; Guo, Q[1,3,*1] ;
机构： [1]Faculty of Medicine,Kunming Universityof Science andTechnology,Kunming 650504,Yunnan, China [2]Instituteof Basic MedicalSciences, The FirstPeople’s Hospital of Yunnan Province,The Affiliated Hospital of KunmingUniversity of Scienceand Technology,Kunming 650504,Yunnan, China [3]Department ofGastroenterology, TheFirst People’s Hospitalof Yunnan Province,The AffiliatedHospital of KunmingUniversity of Scienceand Technology,Kunming 650504,Yunnan, China
出处：
DOI： 10.4103/jcrt.JCRT_701_17
ISSN：

关键词： Epithelial-mesenchymal transition forkhead box Q1 gene signal pathways tumor tumorgenesis

摘要：
Transcription factor forkhead box Q1 (FOXQ1), a member of the forkhead box superfamily, has been involved in various biological processes and plays important roles in tumor initiation and progression. The FOXQ1 protein activated transcription of target genes directly by binding to the promoters of target genes or indirectly by interacting with other transcription factors. FOXQ1 affected the initiation, progression, invasion, and metastasis of many kinds of tumor by promoting the epithelial-mesenchymal transition, regulating cell cycle, promoting cell proliferation, regulating senescence-associated inflammation, and activating many cellular signal pathways. In this review, we have focused on the possible molecular mechanisms for FOXQ1 gene in tumor initiation and progression. Medline literature review related to this subject was performed by the electronically retrieval with the keywords 'forkhead box Q1' and 'tumor' on PubMed for including previous publications, and then, it further reviewed reference articles on the biological function of FOXQ1 gene and target genes transcription directly regulated by FOXQ1. © 2018 Journal of Cancer Research and Therapeutics | Published by Wolters Kluwer - Medknow.

基金：
This study was supported by National Natural Science Foundation of China (Grant No. 81502556 and 81260323), Young Academic Talents Cultivation Foundation of Yunnan Province (Grant No. 2013HB083), and Medical Discipline Leaders Cultivate Fund of Health and Family Planning Commission of Yunnan Province (Grant No. D‑201642).
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2018]版：
大类 | 4 区 医学
小类 | 4 区 肿瘤学
最新[2023]版：
大类 | 4 区 医学
小类 | 4 区 肿瘤学
JCR分区：
出版当年[2017]版：
Q4 ONCOLOGY
最新[2023]版：
Q4 ONCOLOGY

影响因子： 最新[2023版] 最新五年平均 出版当年[2017版] 出版当年五年平均 出版前一年[2016版] 出版后一年[2018版]

第一作者：
第一作者机构： [1]Faculty of Medicine,Kunming Universityof Science andTechnology,Kunming 650504,Yunnan, China [2]Instituteof Basic MedicalSciences, The FirstPeople’s Hospital of Yunnan Province,The Affiliated Hospital of KunmingUniversity of Scienceand Technology,Kunming 650504,Yunnan, China
通讯作者：
通讯机构： [1]Faculty of Medicine,Kunming Universityof Science andTechnology,Kunming 650504,Yunnan, China [3]Department ofGastroenterology, TheFirst People’s Hospitalof Yunnan Province,The AffiliatedHospital of KunmingUniversity of Scienceand Technology,Kunming 650504,Yunnan, China [*1]College of Medicine, Kunming University of Science and Technology, No. 727 South Jingming Road, Chenggong District, Kunming 650504, Yunnan, China
推荐引用方式(GB/T 7714)：
Tang H,Zhang J,Guo Q.Research progress on the regulation of tumor initiation and development by the forkhead box Q1 gene(Open Access)[J].JOURNAL OF CANCER RESEARCH AND THERAPEUTICS.2018,14(1):6-11.doi:10.4103/jcrt.JCRT_701_17.
APA：
Tang, H,Zhang, J&Guo, Q.(2018).Research progress on the regulation of tumor initiation and development by the forkhead box Q1 gene(Open Access).JOURNAL OF CANCER RESEARCH AND THERAPEUTICS,14,(1)
MLA：
Tang, H,et al."Research progress on the regulation of tumor initiation and development by the forkhead box Q1 gene(Open Access)".JOURNAL OF CANCER RESEARCH AND THERAPEUTICS 14..1(2018):6-11

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