Hip-joint CT images have low organizational contrast, irregular shape of boundaries and image noises. Traditional segmentation algorithms often require manual intervention or introduction of some prior information, which results in low efficiency and is unable to meet clinical needs. In order to overcome the sensitivity of classical fuzzy clustering image segmentation algorithm to image noise, this paper proposes a fuzzy clustering image segmentation algorithm combining Gaussian regression model (GRM) and hidden Markov random field (HMRF). The algorithm uses the prior information to regularize the objective function of the fuzzy C-means, and then improves it with KL information. The HMRF model establishes the neighborhood relationship of the label field by prior probability, while CRM model establishes the neighborhood relationship of feature field on the basis of the consistency between the central pixel label and its neighborhood pixel label. The experimental results show that the proposed algorithm has high segmentation accuracy.