Anterior Cervical Spondylosis Surgical Interventions are Associated with Improved Lordosis and Neurological Outcomes at Latest Follow up: A Meta-analysis
机构:[1]Department of Orthopaedics, First People’s Hospital of YunNan Province, YunNan, P. R. China.外科片骨科云南省第一人民医院[2]Department of Rehabilitation Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, P. R. China.[3]Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, P. R. China.[4]Shanghai Key Laboratory of Forensic Medicine, Institute of Forensic Science, Ministry of Justice, Shanghai, P.R. China.
Aim of this study was to evaluate the effect of cervical spondylosis surgery on cervical lordosis and to identify factors affecting the change by latest follow-up. Literature search was carried out in electronic databases and study selection followed a priori eligibility criteria. Random effects meta-analyses were performed to estimate effect size/s of change in lordosis after surgery (at latest follow-up) and metaregression analyses were performed to identify factors affecting this change. Nineteen studies (1845 patients; age 55.18 [95% CI: 54.78, 55.57] years; 60.99 [60.63, 61.36] % males; follow-up 25.59 [25.20, 25.99] months) were included. Whereas, corpectomy (4.06 [2.65, 5.46] degree; p < 0.00001) and discectomy (4.59 [2.07, 7.11] degree; p < 0.00001) were associated with increase, laminectomy (-1.87 [-8.40, 4.66] degree; p = 0.57) and laminoplasty (0.25 [-1.07, 1.56] degree; p = 0.711) were not associated with significant change in lordosis at latest follow-up. Change in Japanese Orthopedic Association (JOA)/modified JOA (mJOA) score at latest follow-up was also significantly (p = 0.0005) higher in anterior than in posterior surgery group. Change in lordosis at latest follow-up had significant positive relationship with follow-up duration but had significant inverse associations with age, male gender, and preoperative JOA/mJOA score, independently. In posterior surgery subjects, after adjusting for age and gender, preoperative JOA/mJOA score was significantly inversely related to change in lordosis.
基金:
National Natural Science Foundation of China (Grant No. 31300137).
第一作者机构:[1]Department of Orthopaedics, First People’s Hospital of YunNan Province, YunNan, P. R. China.
通讯作者:
推荐引用方式(GB/T 7714):
Meng Zengdong,Yu Jing,Luo Chong,et al.Anterior Cervical Spondylosis Surgical Interventions are Associated with Improved Lordosis and Neurological Outcomes at Latest Follow up: A Meta-analysis[J].SCIENTIFIC REPORTS.2017,7:doi:10.1038/s41598-017-04311-6.
APA:
Meng, Zengdong,Yu, Jing,Luo, Chong,Liu, Xia,Jiang, Wei...&Huang, Rongzhong.(2017).Anterior Cervical Spondylosis Surgical Interventions are Associated with Improved Lordosis and Neurological Outcomes at Latest Follow up: A Meta-analysis.SCIENTIFIC REPORTS,7,
MLA:
Meng, Zengdong,et al."Anterior Cervical Spondylosis Surgical Interventions are Associated with Improved Lordosis and Neurological Outcomes at Latest Follow up: A Meta-analysis".SCIENTIFIC REPORTS 7.(2017)