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Combined early dynamic F-18-FDG PET/CT and conventional whole-body F-18-FDG PET/CT provide one-stop imaging for detecting hepatocellular carcinoma

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机构: [1]Southern Med Univ, Nanfang Hosp, NanFang PET Ctr, Guangzhou 510515, Guangdong, Peoples R China [2]First Peoples Hosp Yunnan Prov, Dept Radiol, Kunming, Peoples R China
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Background and objective: It is widely accepted that conventional F-18-FDG PET/CT (whole-body static F-18-FDG PET/CT, WB F-18-FDG PET/CT) has a low detection rate for hepatocellular carcinoma (HCC). We prospectively assessed the role of early dynamic F-18-FDG PET/CT (ED F-18-FDG PET/CT) and WB F-18-FDG PET/CT in detecting HCC, and we quantified the added value of ED F-18-FDG PET/CT to WB F-18-FDG PET/CT. Methods: Twenty-two patients with 37 HCC tumors (HCCs) who underwent both a liver ED F-18-FDG PET/CT (performed simultaneously with a 5.5 MBq/kg F-18-FDG bolus injection and continued for 240 s) and a WB F-18-FDG PET/CT were enrolled in the study. Results: The WB F-18-FDG PET/CT and ED F-18-FDG PET/CT scans were positive in 56.7% (21/37) and 78.4% (29/37) HCCs, respectively (P < 0.05). ED F-18-FDG PET/CT in conjunction with WB F-18-FDG PET/CT (one-stop F-18-FDG PET/CT) improved the positive detection rates of WB and ED F-18-FDG PET/CT alone from 56.7% and 78.4% to 91.9% (34/37) (P < 0.001 and P > 0.05, respectively). Conclusion: One-stop F-18-FDG PET/CT appears to be useful to improve WB F-18-FDG PET/CT for HCC detection. (C) 2014 Elsevier Masson SAS. All rights reserved.

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出版当年[2015]版:
大类 | 4 区 医学
小类 | 4 区 胃肠肝病学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 胃肠肝病学
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出版当年[2014]版:
Q4 GASTROENTEROLOGY & HEPATOLOGY
最新[2023]版:
Q2 GASTROENTEROLOGY & HEPATOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2014版] 出版当年五年平均 出版前一年[2013版] 出版后一年[2015版]

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第一作者机构: [1]Southern Med Univ, Nanfang Hosp, NanFang PET Ctr, Guangzhou 510515, Guangdong, Peoples R China [2]First Peoples Hosp Yunnan Prov, Dept Radiol, Kunming, Peoples R China
通讯作者:
通讯机构: [1]Southern Med Univ, Nanfang Hosp, NanFang PET Ctr, Guangzhou 510515, Guangdong, Peoples R China [*1]NanFang PET Center, Nanfang Hospital, Southern Medical University, 1838, Guangzhou Avenue North, Guangzhou,Guangdong Province, 510515, China
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