The aim of this paper is to summarise the blocking effects of parthenolide on the cytokines and pathways that cause inflammation. Analyses of the chemical structure of parthenolide have tried to identify the active domains that play key roles in its anti-inflammatory activity. This review focuses on the anti-inflammatory actions of parthenolide in both in vitro and in vivo. These data will be helpful for future investigations into the effects of parthenolide on inflammation.
基金:
National Scientific Foundation of China under National Scientific Grant [81160134]; Yunnan Provincial Science and Technology Department under Grant Talent Reserve of Young Academic and Technical Leaders of Yunnan Province [2012HB027]; Yunnan Provincial Bureau of Health under Grant Medical Academic Leaders of Yunnan Province [D-201232]
第一作者机构:[1]Kunming Univ Sci & Technol, Fac Med, Kunming, Peoples R China[2]Kunming Univ Sci & Technol, Affiliated Hosp, Kunming, Peoples R China
通讯作者:
通讯机构:[1]Kunming Univ Sci & Technol, Fac Med, Kunming, Peoples R China[2]Kunming Univ Sci & Technol, Affiliated Hosp, Kunming, Peoples R China[3]First Peoples Hosp Yunnan Prov, Kunming, Peoples R China
推荐引用方式(GB/T 7714):
Wang Mengting,Li Qiyan.Parthenolide could become a promising and stable drug with anti-inflammatory effects[J].NATURAL PRODUCT RESEARCH.2015,29(12):1092-1101.doi:10.1080/14786419.2014.981541.
APA:
Wang, Mengting&Li, Qiyan.(2015).Parthenolide could become a promising and stable drug with anti-inflammatory effects.NATURAL PRODUCT RESEARCH,29,(12)
MLA:
Wang, Mengting,et al."Parthenolide could become a promising and stable drug with anti-inflammatory effects".NATURAL PRODUCT RESEARCH 29..12(2015):1092-1101