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Detection of Antiphospholipid Antibody in Children With Henoch-Schonlein Purpura and Central Nervous System Involvement

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收录情况: ◇ SCIE

机构: [1]Department of Pediatrics, Peking University First Hospital, Beijing, China [2]Department of Pediatrics, First People’s Hospital of Yunnan Province, Kunming, China
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摘要:
To explore the mechanisms of central nervous system involvement in children with Henoch-Schonlein purpura, levels of lupus anticoagulant, anticardiolipin antibodies, and anti-beta 2 glycoprotein I antibodies in serum and cerebrospinal fluid were determined in 46 cases of Henoch-Schotilein purpura with central nervous system involvement. Results indicated that Henoch-Schonlein purpura with central nervous system involvement produced a higher total percentage of antiphospholipid antibodies in serum and cerebrospinal fluid, compared with viral encephalitis control subjects (76.1% vs 10.0% and 71.7% vs 0.0%, respectively; P < 0.05). Henoch-Schonlein purpura may be associated with antiphospholipid syndrome or antiphospholipid antibodies, which may account for the neurologic damage in Henoch-Schonlein purpura. (C) 2012 Elsevier Inc. All rights reserved.

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出版当年[2012]版:
大类 | 4 区 医学
小类 | 3 区 儿科 4 区 临床神经病学
最新[2025]版:
大类 | 3 区 医学
小类 | 2 区 儿科 3 区 临床神经病学
JCR分区:
出版当年[2011]版:
Q2 PEDIATRICS Q3 CLINICAL NEUROLOGY
最新[2023]版:
Q1 PEDIATRICS Q2 CLINICAL NEUROLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2011版] 出版当年五年平均 出版前一年[2010版] 出版后一年[2012版]

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第一作者机构: [1]Department of Pediatrics, Peking University First Hospital, Beijing, China [2]Department of Pediatrics, First People’s Hospital of Yunnan Province, Kunming, China
通讯作者:
通讯机构: [1]Department of Pediatrics, Peking University First Hospital, Beijing, China [*1]Department of Pediatrics ,Peking University First Hospital , No. 1, Xi An Men Da Jie ,Beijing 100034, People’s Republic of China
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