机构：[a]School of Materials Science and Engineering, Kunming University of Science and Technology, Kunming, 650093, China[b]Department of Orthopedics, First People's Hospital of Yunnan Province, Kunming, 650032, China外科片骨科云南省第一人民医院[c]Department of Pathology, First people'Shospital of Yunnan Province, Kunming, 650032, China
In this work, the porous hydroxyapatite (HA) bone repair materials were fabricated by spark plasma sintering (SPS) at pressureless conditions with the addition of ammonium bicarbonate (NH4HCO3)at 1050 °C. Porous characteristic, mechanical properties and biocompatibility of the porous HA were investigated. The results showed that 43.8%-69.3% porosity and 100-500 μm pore size of the porous HA could be obtained by the addition of NH4HCO3from 10-30 wt.%. The elastic modulus of the porous HA was in the range of 142.5-48.6 MPa and the compression strength range from 4.6 to 1.1 MPa. The biologic test showed that the porous HA exhibited good biocompatibility. Rabbit bone marrow stromal cells validated the celluar acceptance of the surfaces of porous samples. In summary, the porous HA has preferable porosity, pore structures, mechanical properties and good biocompatibility by the SPStechnique. Therefore, it was favorable to osteoconduction and the osteogenic activity.
语种：
外文
第一作者：
第一作者机构：[a]School of Materials Science and Engineering, Kunming University of Science and Technology, Kunming, 650093, China
推荐引用方式(GB/T 7714)：
Zhang Y,Zhang L,Meng Z,et al.Biocompatibility and mechanical properties of porous hydroxyapatite bone repair materials fabricated by spark plasma sintering[J].2016,
APA：
Zhang, Y,Zhang, L,Meng, Z&Luo, L.(2016).Biocompatibility and mechanical properties of porous hydroxyapatite bone repair materials fabricated by spark plasma sintering.,,
MLA：
Zhang, Y,et al."Biocompatibility and mechanical properties of porous hydroxyapatite bone repair materials fabricated by spark plasma sintering". .(2016)
