机构：[a]Faculty of Life Science and Technology, Kunming University of Science and Technology, Chenggong Campus, Kunming, Yunnan, China[b]Cadres Treatment Section,The First People's Hospital of Yunnan Province,Panlong Campus,Kunming,Yunnan,China云南省第一人民医院[c]Thoracic Surgery,The First People's Hospital of Yunnan Province,Panlong Campus,Kunming,Yunnan,China外科片胸外科云南省第一人民医院
In order to explore the association between cadherin 13 (CDH13) gene promoter methylation and lung carcinoma (LC) risk, we carried out a meta-analysis with searching of PubMed, Web of Science. Ultimately, 17 articles were identified and analysised by STATA 12.0 software. Overall, we found a significant relationship between CDH13 promoter methylation and LC risk (odds ratio=6.98, 95% confidence interval: 4.21-11.56, p<0.001). Subgroup analyses further revealed that LC risk was increased for individuals carrying the methylated CDH13 compared with those with unmethylated CDH13. Hence, our study identified a strong association between CDH13 gene promoter methylation and LC and highlighted a promising potential for CDH13 methylation in LC risk prediction.
基金：
Specialized Research Fund for Yunnan province (2013FB197) (No.
20115314110005)
语种：
外文
中科院(CAS)分区：
出版当年[2015]版：
大类|4 区医学
小类|4 区肿瘤学
最新[2025]版：
无
第一作者：
第一作者机构：[a]Faculty of Life Science and Technology, Kunming University of Science and Technology, Chenggong Campus, Kunming, Yunnan, China[b]Cadres Treatment Section,The First People's Hospital of Yunnan Province,Panlong Campus,Kunming,Yunnan,China
通讯作者：
推荐引用方式(GB/T 7714)：
Zhong Y.-H,Peng H,Cheng H.-Z,et al.Quantitative assessment of the diagnostic role of CDH13 promoter methylation in lung cancer(Open Access)[J].Asian Pacific Journal of Cancer Prevention.2015,16(3):doi:10.7314/APJCP.2015.16.3.1139.
APA：
Zhong, Y.-H,Peng, H,Cheng, H.-Z&Wang, P.(2015).Quantitative assessment of the diagnostic role of CDH13 promoter methylation in lung cancer(Open Access).Asian Pacific Journal of Cancer Prevention,16,(3)
MLA：
Zhong, Y.-H,et al."Quantitative assessment of the diagnostic role of CDH13 promoter methylation in lung cancer(Open Access)".Asian Pacific Journal of Cancer Prevention 16..3(2015)
