机构：[a]Faculty of Life Science and Technology, Kunming University of Science and Technology, Chenggong Campus, Kunming, Yunnan, China[b]Cadres Treatment Section, The First People's Hospital of Yunnan Province, Panlong Campus, Kunming, Yunnan, China云南省第一人民医院[c]Thoracic Surgery, The First People's Hospital of Yunnan Province, Panlong Campus, Kunming, Yunnan, China外科片胸外科云南省第一人民医院
In order to explore the association between cadherin 13 (CDH13) gene promoter methylation and lung carcinoma (LC) risk, we carried out a meta-analysis with searching of PubMed, Web of Science. Ultimately, 17 articles were identified and analysised by STATA 12.0 software. Overall, we found a significant relationship between CDH13 promoter methylation and LC risk (odds ratio=6.98, 95% confidence interval: 4.21-11.56, p<0.001). Subgroup analyses further revealed that LC risk was increased for individuals carrying the methylated CDH13 compared with those with unmethylated CDH13. Hence, our study identified a strong association between CDH13 gene promoter methylation and LC and highlighted a promising potential for CDH13 methylation in LC risk prediction.
基金：
Specialized Research Fund for Yunnan province (2013FB197) (No.
20115314110005)
语种：
外文
中科院(CAS)分区：
出版当年[2015]版：
大类|4 区医学
小类|4 区肿瘤学
最新[2023]版：
无
第一作者：
第一作者机构：[a]Faculty of Life Science and Technology, Kunming University of Science and Technology, Chenggong Campus, Kunming, Yunnan, China[b]Cadres Treatment Section, The First People's Hospital of Yunnan Province, Panlong Campus, Kunming, Yunnan, China
通讯作者：
推荐引用方式(GB/T 7714)：
Zhong Y.-H,Peng H,Cheng H.-Z,et al.Quantitative assessment of the diagnostic role of CDH13 promoter methylation in lung cancer(Open Access)[J].Asian Pacific Journal of Cancer Prevention.2015,16(3):doi:10.7314/APJCP.2015.16.3.1139.
APA：
Zhong, Y.-H,Peng, H,Cheng, H.-Z&Wang, P.(2015).Quantitative assessment of the diagnostic role of CDH13 promoter methylation in lung cancer(Open Access).Asian Pacific Journal of Cancer Prevention,16,(3)
MLA：
Zhong, Y.-H,et al."Quantitative assessment of the diagnostic role of CDH13 promoter methylation in lung cancer(Open Access)".Asian Pacific Journal of Cancer Prevention 16..3(2015)
