机构：[a]Medical Faculty, Kunming University of Science and Technology, China[b]Digestive System Department, The First People's Hospital of Yunnan Province, Panlong Campus, 157 Jinbi Road, Kunming, Yunnan, China内科片消化内科云南省第一人民医院[c]Clinical Psychology Department, The First People's Hospital of Yunnan Province, Panlong Campus, 157 Jinbi Road, Kunming, Yunnan, China内科片临床心理科云南省第一人民医院
In order to explore the association between RASSF1A methylation and nasopharyngeal carcinoma (NPC)risk of Chinese, we carried out a meta-analysis with searches of PubMed, Web of Science, ProQest and Medline databases. Ultimately, 14 articles were identified and analysised using R Software (R version 3.1.2) including meta packages. Overall, we found a significant relationship between RASSF1A methylation and NPC risk (OR 30.7; 95 % CI, 16.71~56.23; z=11.0591; p<0.0001) in a fixed effects model and (OR 32.1; 95% CI, 14.27~72.01; z=8.3984; p<0.0001) in a random effects model pooled. In tissue and NP brushings groups, similar results were found. Hence, our study identified a strong association between RASSF1A methylation and NPC and highlighted a promising potential for RASSF1A methylation in NPC risk prediction of Chinese.
基金：
Applied Basic Research Projects of Yunnan Province
(No.2013FB206)
语种：
外文
中科院(CAS)分区：
出版当年[2015]版：
大类|4 区医学
小类|4 区肿瘤学
最新[2023]版：
无
第一作者：
第一作者机构：[a]Medical Faculty, Kunming University of Science and Technology, China[b]Digestive System Department, The First People's Hospital of Yunnan Province, Panlong Campus, 157 Jinbi Road, Kunming, Yunnan, China
通讯作者：
推荐引用方式(GB/T 7714)：
Wu K,Xu X.-N,Chen Y,et al.RASSF1A gene methylation is associated with nasopharyngeal carcinoma risk in Chinese(Open Access)[J].Asian Pacific Journal of Cancer Prevention.2015,16(6):doi:10.7314/APJCP.2015.16.6.2283.
APA：
Wu, K,Xu, X.-N,Chen, Y,Pu, X.-L,Wang, B.-Y&Tang, X.-D.(2015).RASSF1A gene methylation is associated with nasopharyngeal carcinoma risk in Chinese(Open Access).Asian Pacific Journal of Cancer Prevention,16,(6)
MLA：
Wu, K,et al."RASSF1A gene methylation is associated with nasopharyngeal carcinoma risk in Chinese(Open Access)".Asian Pacific Journal of Cancer Prevention 16..6(2015)
