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Protective effect of daizein on apoptosis cells of nasal mucosas in ovariectomized rats

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收录情况: ◇ 北大核心 ◇ 中华系列

机构: [1]Department of Otorhinolaryngology, First People's Hospital of Yunnan Province, Kunming, 650001, China
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摘要:
OBJECTIVE: To study the protective effect of daizein on apoptosis cells of atrophic nasal mucosas in ovariectomized rats. METHODS: Sixty rats were divided into four groups as contrary, ovariectomized, ovariectomized + nylestriol (O + N) and ovariectomized + daizein (O + D), each with 15 rats. Earlier apotosis cells of nasal mucosas taken from nasal septum were measured with flow cytometry. RESULTS: Compared with contrary group, the number of apoptosis cells of mucosas increased after being ovariectomized, the number of apoptosis cells of mucosas in O + N and O + D groups didn't change. CONCLUSION: Estrogen replacement and daizein might have effects on protecting cells of mucosas from lacking of estrogen by decreasing apoptosis cells in ovariectomized rats.

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第一作者机构: [1]Department of Otorhinolaryngology, First People's Hospital of Yunnan Province, Kunming, 650001, China
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