机构：[1]Yunnan Key Laboratory of Primate Biomedical Research, Institute of Primate[2]PET/CT center, First People’s Hospital of Yunnan Province, Kunming, China医技片PET/CT云南省第一人民医院[3]PET-CT Center, Yunnan Cancer Hospital, Kunming, China.
We aimed to differentiate tuberculous peritonitis (TBP) from peritoneal carcinomatosis (PC) using a visual positron-emission tomography/computed tomography (PET/CT) scoring system based on mesenteric fluorodeoxyglucose (FDG) uptake.
PET/CT scans from 31 patients with TBP and 92 patients with PC were retrospectively reviewed. A visual PET/CT scoring system for mesenteric FDG uptake was used according to the following characteristics: FDG uptake intensity (low = 0, moderate = 1, high = 2), FDG uptake deposits (uniform = 0, irregular = 1, ascitic = 2), FDG uptake focality (diffuse = 0, segmental = 1, focal = 2), nodularity on the corresponding CT (nonnodular = 0, micronodular = 1, macronodular = 2) and mesenteric lymphadenopathy (absent = 0, lymphadenopathy without FDG uptake = 1, lymphadenopathy with FDG uptake = 2). The FDG uptake intensity, deposits, focality, nodularity and mesenteric lymphadenopathy scores between TBP and PC were compared using chi-square tests. The diagnostic performance of this scoring system for differentiating TBP from PC was analyzed using a receiver operating characteristic (ROC) curve. P <0.05 was considered statistically significant.
Twenty-four patients with TBP (77.4%) and 56 patients with PC (60.9%) had mesenteric FDG uptake (P = 0.095) and were included for evaluation with the visual PET/CT scoring system. PC lesions scored higher than TBP lesions in FDG uptake deposits (P < 0.001), focality (P < 0.001) and nodularity (P < 0.001). No significant differences were observed between PC and TBP lesions in FDG uptake intensity (P = 0.396) and lymphadenopathy (P = 0.074). The total score that combined deposits, focality and nodularity had significant value for differentiating TBP from PC (area under the curve (AUC) = 0.869, P < 0.001), and a cutoff > 1 had a sensitivity (the accuracy for diagnosis of PC) of 80.4% and a specificity (the accuracy for diagnosis of TBP) of 75.0%.
A visual PET/CT scoring system based on mesenteric FDG uptake performed well in differentiating between TBP and PC.
基金：
1. National Natural Science Foundation of China, No. 81760306;
2. Basic Research on Application of Joint Special Funding of Science and Technology Department of Yunnan Province-Kunming Medical University, No. 2018FE001(-291);
3. Science Research Foundation of Yunnan Educational Agency, No. 2019J1286;
4. High-level Talent Project of Health in Yunnan Province, No. D-2018011;
5. Ten Thousand People Plan in Yunnan Province No. YNWR-QNBJ-2018-243.
第一作者机构：[1]Yunnan Key Laboratory of Primate Biomedical Research, Institute of Primate[2]PET/CT center, First People’s Hospital of Yunnan Province, Kunming, China
通讯作者：
推荐引用方式(GB/T 7714)：
Shao-bo Wang,Hong He,Dong-dong Xv,et al.Visual PET/CT scoring of mesenteric fdg uptake to differentiate between tuberculous peritonitis and peritoneal carcinomatosis.[J].DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY.2020,26(6):523-530.doi:10.5152/dir.2020.20088.
APA：
Shao-bo Wang,Hong He,Dong-dong Xv,Bo She,Ren-cai Lu...&Ran Xie.(2020).Visual PET/CT scoring of mesenteric fdg uptake to differentiate between tuberculous peritonitis and peritoneal carcinomatosis..DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY,26,(6)
MLA：
Shao-bo Wang,et al."Visual PET/CT scoring of mesenteric fdg uptake to differentiate between tuberculous peritonitis and peritoneal carcinomatosis.".DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY 26..6(2020):523-530
