机构:[1]Department of Geriatric Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province. China.昆明医科大学附属第一医院[2]Institute of sports science, Sichuan University, No.24 South Section 1, Yihuan Road, Chengdu, Sichuan Province. China.[3]Department of Periodical Press and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu. China.四川大学华西医院
Neurodegenerative diseases are caused by progressive lesions or loss of specific nerve cells, which endanger human health. However, the mechanism by which neurodegeneration manifests remains unclear. Proteomics can shed light on this question as well as help establish diagnostic standards and discover new drug targets. The power of proteomics for understanding neurodegenerative diseases has increased substantially with the application of iTRAQ and TMT labeling techniques. This review focuses on progress in these labeling techniques and their applications in neurodegeneration research.
基金:
the National Natural Science
Foundation of China with grant numbers 81960242 and
81860247
第一作者机构:[1]Department of Geriatric Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province. China.
共同第一作者:
通讯作者:
通讯机构:[3]Department of Periodical Press and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu. China.[*1]Department of Geriatric Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, P.R. China
推荐引用方式(GB/T 7714):
Li Kelu,Chen Zichao,Yang Xinglong,et al.Applications of iTRAQ and TMT labeling techniques to the study of neurodegenerative diseases.[J].CURRENT PROTEIN & PEPTIDE SCIENCE.2020,21(12):1202-1217.doi:10.2174/1389203721666201103085704.
APA:
Li Kelu,Chen Zichao,Yang Xinglong&Zhang Yonggang.(2020).Applications of iTRAQ and TMT labeling techniques to the study of neurodegenerative diseases..CURRENT PROTEIN & PEPTIDE SCIENCE,21,(12)
MLA:
Li Kelu,et al."Applications of iTRAQ and TMT labeling techniques to the study of neurodegenerative diseases.".CURRENT PROTEIN & PEPTIDE SCIENCE 21..12(2020):1202-1217