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Applications of iTRAQ and TMT labeling techniques to the study of neurodegenerative diseases.

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机构: [1]Department of Geriatric Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province. China. [2]Institute of sports science, Sichuan University, No.24 South Section 1, Yihuan Road, Chengdu, Sichuan Province. China. [3]Department of Periodical Press and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu. China.
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关键词: Neurodegenerative diseases Proteomics Quantitative neuroproteomics TMT iTRAQ

摘要:
Neurodegenerative diseases are caused by progressive lesions or loss of specific nerve cells, which endanger human health. However, the mechanism by which neurodegeneration manifests remains unclear. Proteomics can shed light on this question as well as help establish diagnostic standards and discover new drug targets. The power of proteomics for understanding neurodegenerative diseases has increased substantially with the application of iTRAQ and TMT labeling techniques. This review focuses on progress in these labeling techniques and their applications in neurodegeneration research.

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出版当年[2020]版
大类 | 4 区 生物
小类 | 4 区 生化与分子生物学
最新[2023]版
大类 | 4 区 生物学
小类 | 4 区 生化与分子生物学
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出版当年[2019]版:
Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY
最新[2023]版:
Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2019版] 出版当年五年平均 出版前一年[2018版] 出版后一年[2020版]

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第一作者机构: [1]Department of Geriatric Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province. China.
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通讯机构: [3]Department of Periodical Press and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu. China. [*1]Department of Geriatric Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, 650032, P.R. China
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