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The comparison of microbial communities in thyroid tissues from thyroid carcinoma patients.

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机构: [1]Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, Yunnan, P. R. China [2]Gastroenterology Department, the First People’s Hospital of Yunnan Province, Kunming 650032, Yunnan, P. R. China [3]Gastroenterology Department, the Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, Yunnan,P. R. China [4]Oncology Department, the First People’s Hospital of Yunnan Province,Kunming 650032, Yunnan, P. R. China [5]Oncology Department, The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, Yunnan, P. R. China
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Thyroid carcinoma is a common endocrine organ cancer associated with abnormal hormone secretion, leading to the disorder of metabolism. The intestinal microbiota is vital to maintain digestive and immunologic homeostasis. The relevant information of the microbial community in the gut and thyroid, including composition, structure, and relationship, is unclear in thyroid carcinoma patients. A total of 93 samples from 25 patients were included in this study. The results showed that microbial communities existed in thyroid tissue; gut and thyroid had high abundance of facultative anaerobes from the Proteobacteria phyla. The microbial metabolism from the thyroid and gut may be affected by the thyroid carcinoma cells. The cooccurrence network showed that the margins of different thyroid tissues were unique areas with more competition; the stabilization of microcommunities from tissue and stool may be maintained by several clusters of species that may execute different vital metabolism processes dominantly that are attributed to the microenvironment of cancer.© 2021. The Microbiological Society of Korea.

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出版当年[2021]版:
大类 | 3 区 生物
小类 | 4 区 微生物学
最新[2023]版:
大类 | 4 区 生物学
小类 | 4 区 微生物学
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出版当年[2020]版:
Q3 MICROBIOLOGY
最新[2023]版:
Q2 MICROBIOLOGY

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第一作者机构: [1]Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, Yunnan, P. R. China
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通讯机构: [4]Oncology Department, the First People’s Hospital of Yunnan Province,Kunming 650032, Yunnan, P. R. China [5]Oncology Department, The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, Yunnan, P. R. China
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