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Efficacy and Safety of Sorafenib as Adjuvant and Latter Radiofrequency Ablation for Recurrent Hepatocellular Carcinoma

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研究单位： [1]Southwest Hospital, China [2]Chengdu PLA General Hospital [3]Sichuan Provincial People's Hospital [4]Sichuan Cancer Hospital and Research Institute [5]Hunan Cancer Hospital [6]Cancer Hospital of Guangxi Medical University [7]The First People's Hospital of Yunnan [8]Yunnan Cancer Hospital [9]Xiangya Hospital of Central South University [10]Xinqiao Hospital of Chongqing [11]The Second Affiliated Hospital of Chongqing Medical University [12]Henan Cancer Hospital [13]First Affiliated Hospital of Chongqing Medical University [14]First Affiliated Hospital of Guangxi Medical University

研究目的：

Radiofrequency ablation is a popular treatment for recurrent hepatocellular carcinoma (HCC),but still has a higher recurrence. Sorafenib as neo-adjuvant therapy in combination of RFA was not reported yet. There's a theoretical advantage of this combination. Hence in this study the efficacy and safety of pre-administrative Sorafenib and Latter radiofrequency ablation (RFA) in Recurrent HCC will be tested in a multicenter prospective cohort study.

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