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A Study to Evaluate Efficacy and Long-term Safety of Oral Ozanimod in Chinese Participants With Moderately to Severely Active Ulcerative Colitis (UC)

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研究单位: [1]Bristol-Myers Squibb [2]Anhui Provincial Hospital,Hefei,Anhui,China,230071 [3]Wannan Medical College Yijishan Hospital,Wuhu,Anhui,China,241001 [4]Peking University International Hospital,Beijing,Beijing,China,102206 [5]Chongqing General Hospital,Chongqing,Chongqing,China,400014 [6]Zhongshan Hospital Affiliated to Xiamen University,Xiamen,Fujian,China,361004 [7]Local Institution - 0020,Guangzhou,Guangdong,China,510080 [8]Guangzhou First People's Hospital,Guangzhou,Guangdong,China,510180 [9]Zhujiang Hospital,Guangzhou,Guangdong,China,510280 [10]Southern Medical University Nanfang Hospital,Guangzhou,Guangdong,China,510515 [11]The Sixth Affiliated Hospital of Sun Yat-sen University,Guangzhou,Guangdong,China,510655 [12]Affiliated Hospital of Guangdong Medical University,Zhanjiang,Guangdong,China,524004 [13]Affiliated Hospital of Guilin Medical University,Guilin,Guangxi,China,541001 [14]Local Institution - 0023,Nanning,Guangxi,China,530021 [15]The Second Afilliated Hospital of Hebei Medical University,Shijiazhuang,Hebei,China,050000 [16]Shijiazhuang People's Hospital,Shijiazhuang,Hebei,China,050011 [17]Union Hospital Tongji Medical College Huazhong University of Science and Technology,Wuhan,Hubei,China,430022 [18]Tongji Hospital Tongji Medical,Science & Technology,Wuhan,Hubei,China,430030 [19]Renmin Hospital of Wuhan University,Wuhan,HUB,China,430060 [20]Xiangya Hospital Central South University,Changsha,Hunan,China,410008 [21]The Third Xiangya Hospital of Central South University,Changsha,Hunan,China,410013 [22]Changzhou No.2 People's Hospital,Changzhou,Jiangsu,China,0 [23]The First People's Hospital of Changzhou,Changzhou,Jiangsu,China,213003 [24]Local Institution - 0024,Nanjing,Jiangsu,China,210000 [25]Jiangsu Province Hospital,Nanjing,Jiangsu,China,210029 [26]The Second Affiliated Hospital of Soochow University,Suzhou,Jiangsu,China,215004 [27]Local Institution - 0009,Suzhou,Jiangsu,China,215006 [28]Wuxi People's Hospital,Wuxi,Jiangsu,China,214023 [29]Affiliated Hospital of Jiangsu University,Zhenjiang,Jiangsu,China,212000 [30]Shengjing Hospital of China Medical University,Shenyang,Liaoning,China,110004 [31]Xijing Hospital,Xi'an,Shaanxi,China,710032 [32]Tangdu Hospital of Fourth Military Medical University of Chinese People's Liberation Army,Xi'an,Shaanxi,China,710038 [33]Qilu Hospital of Shandong University (Qingdao),Jinan,Shandong,China,250014 [34]Ruijin Hospital Shanghai Jiaotong University School of Medicine,Shanghai,Shanghai,China,200025 [35]Zhongshan Hospital,Fudan University,Shanghai,Shanghai,China,200032 [36]Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Shanghai,Shanghai,China,200092 [37]Second Hospital of Shanxi Medical University,Taiyuan,Shanxi,China,030001 [38]West China Hospital of Sichuan University,Cheng Du,Sichuan,China,610041 [39]Sichuan Provincial People's Hospital,Chengdu,Sichuan,China,610072 [40]Tianjin Medical University General Hospital,Tianjin,Tianjin,China,300052 [41]Tianjin People' s Hospital,Tianjin,Tianjin,China,300121 [42]The First People's Hospital of Yunnan Province,Kunming,Yunnan,China,650034 [43]Sir Run Run Shaw Hospital of Zhejiang University School of Medicine,Hangzhou,Zhejiang,China,310016 [44]The First Affiliated Hospital Of Fujian Medical University,Fuzhou,China,350005 [45]Shanghai East Hospital,Shanghai,China,200120 [46]Changhua Christian Hospital,Changhua County,Changhua,Taiwan,50006 [47]Local Institution - 0060,Taipei City,Taipei,Taiwan,114 [48]Taipei Medical University Shuang Ho Hospital,New Taipei,Taiwan,235 [49]Local Institution - 0001,Taichung,Taiwan,40447 [50]Local Institution - 0059,Taichung,Taiwan,407 [51]Local Institution - 0056,Taipei,Taiwan,10002 [52]Taipei Veterans General Hospital,Taipei,Taiwan,11217 [53]Chang Gung Medical Foundation-Linkou Branch,Taoyuan,Taiwan,333

研究目的:
The purpose of this study is to evaluate the efficacy and safety of ozanimod compared with placebo in participants with ulcerative colitis (UC) in mainland China and Taiwan. The main study is composed of an induction period, maintenance period, safety follow-up, and participants meeting certain criteria will be given the opportunity to participate in an optional open label extension.

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