研究单位:[1]Eli Lilly and Company[2],Spain,15006[3],Spain,15405[4],Spain,08041[5]Arizona Research Center,Phoenix,Arizona,United States,85053[6]Artemis Institute for Clinical Research,San Diego,California,United States,92103[7]Chase Medical Research, LLC,Waterbury,Connecticut,United States,06708[8]Suncoast Research Group,Miami,Florida,United States,33135[9]North Georgia Clinical Research,Woodstock,Georgia,United States,30189[10]Elite Clinical Trials,Blackfoot,Idaho,United States,83221[11]Northwestern University,Chicago,Illinois,United States,60611[12]MedVadis Research Corporation,Waltham,Massachusetts,United States,02451[13]Great Lakes Research Group, Inc.,Bay City,Michigan,United States,48706[14]Clinvest Research LLC,Springfield,Missouri,United States,65807[15]Mercy Family Clinic,Dallas,Texas,United States,75211[16]Clinical Trials of Texas, Inc.,San Antonio,Texas,United States,78229[17]Northwest Clinical Research Center,Bellevue,Washington,United States,98007[18]Paratus Clinical Research Canberra,Bruce,Australian Capital Territory,Australia,2617[19]Paratus Clinical Research Western Sydney,Blacktown,New South Wales,Australia,2148[20]Emeritus Research,Botany,New South Wales,Australia,2019[21]Royal Brisbane and Women's Hospital,Brisbane,Queensland,Australia,4029[22]Core Research Group,Brisbane,Queensland,Australia,4064[23]CDH Research Institute,Maroochydore,Queensland,Australia,4558[24]Emeritus Research,Camberwell,Victoria,Australia,3124[25]Barwon Health,Geelong,Victoria,Australia,3220[26]Advara HeartCare Joondalup,Joondalup,Western Australia,Australia,6027[27]C-health Research,Calgary,Alberta,Canada,T2V 4J2[28]Eastern Health - General Hospital,St. John's,Newfoundland and Labrador,Canada,A1B 3V6[29]Viable Clinical Research,Bridgewater,Nova Scotia,Canada,B4V 3N2[30]Bluewater Clinical Research Group Inc.,Sarnia,Ontario,Canada,N7T 4X3[31]Viable Clinical Research,Scarborough,Ontario,Canada,M1P 2T7[32]Stouffville Medical Centre,Stouffville,Ontario,Canada,L4A 1H2[33]Private Practice - Dr. Pierre Bonin,Sudbury,Ontario,Canada,P3A 1Y8[34]Canadian Phase Onward,Toronto,Ontario,Canada,M3J 0K2[35]Alpha Recherche Clinique,Quebec,Canada,G2J 0C4[36]ALPHA Recherche Clinique,Quebec,Canada,G3K 2P8[37]Chinese PLA General Hospital,Beijing,Beijing,China,100853[38]Shunde Hospital of Southern Medical Univesity,Foshan,Guangdong,China,528399[39]Cangzhou People's Hospital Medical College,Cangzhou,Hebei,China,061600[40]The First Affiliated Hospital of Henan University of Science &Technology,Luoyang,Henan,China,471003[41]Baotou Central Hospital,Baotou,Inner Mongolia,China,014040[42]Nanjing First Hospital,Nanjing,Jiangsu,China,210006[43]The Second Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu,China,210011[44]Affiliated Hospital of Jiangsu University,Zhenjiang,Jiangsu,China,212000[45]The First Hospital of Jilin University,Changchun,Jilin,China,130021[46]The Fourth Hospital of Harbin Medical University,Harbin,Nangang District,China,150001[47]The First Affiliated Hospital of Xi'an Medical University,Xi'an,Shaanxi,China,710077[48]Jinan Central Hospital,Jinan,Shandong,China,250013[49]Shanghai Minhang District Central Hospital,Shanghai,Shanghai,China,201199[50]Jiading District Central Hospital,Shanghai,Shanghai,China,201800[51]West China Hospital of Sichuan University,Chengdu,Sichuan,China,610041[52]Tianjin Medical University General Hospital,Tianjin,Tianjin,China,300052[53]The First People's Hospital of Yunnan Province,Kunming,Yunnan,China,650034[54]Zhejiang Provincial People's Hospital,Hangzhou,Zhejiang,China,310014[55]Consultorio Médico,Guadalajara,Jalisco,Mexico,44210[56]IMED Internal Medicine Clin Trials,Monterrey,Nuevo León,Mexico,64060[57]Clínica García Flores SC,Monterrey,Nuevo León,Mexico,64610[58]Unidad Médica para la Salud Integral,San Nicolás de los Garza,Nuevo León,Mexico,66465[59]Centro de Estudios de Investigacion Metabolicos y Cardiovasculares, S.C.,Ciudad Madero,Tamaulipas,Mexico,89440[60]Köhler & Milstein Research,Mérida,Yucatán,Mexico,97070[61]Investigacion y Biomedicina de Chihuahua,Chihuahua,Mexico,31000[62]Hu Reina Sofia,Cordoba,Andalucía,Spain,14004[63]Hospital Quirón Málaga,Málaga,Andalucía,Spain,29004[64]Hospital Universitario Infanta Sofía,San Sebastián de Los Reyes,Madrid, Comunidad De,Spain,28702[65]Hospital General Universitario de Valencia,Valencia,Valenciana, Comunitat,Spain,46014[66]Clínica nuevas Tecnologías en Diabetes y Endocrinología (NTDE),Sevilla,Spain,41003[67]Leicester General Hospital,Leicester,Leicestershire,United Kingdom,LE5 4PW[68]Panthera Biopartners - North London,Enfield Town,London, City Of,United Kingdom,EN3 4GS[69]Panthera Biopartners - Sheffield,Sheffield,United Kingdom,S2 5FX
研究目的:
The main purpose of this study is to evaluate the safety and efficacy of retatrutide once-weekly in participants who have obesity or are overweight and have osteoarthritis (OA) of the knee. The study will lasts about 77 weeks.