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Moxibustion for the Prevention of Hemorrhagic Cystitis After Allo-HSCT

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研究单位: [1]Wuhan Union Hospital, China [2]Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou,Hangzhou,Zhe Jiang,China,311121 [3]The First Affiliated Hospital of Zhengzhou University [4]First Affiliated Hospital of Zhejiang University [5]Department of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou,Zhengzhou,He Nan,China,450002 [6]Yi Zhang,Wuhan,Hubei,China,430000 [7]Hematology Department, The First People''s Hospital of Yunnan,Kunming,Yun nan,China,650032

研究目的:
This study was a prospective, multicenter, randomized controlled clinical study planned to recruit 266 hematological patients with allogeneic hematopoietic stem cell transplantation (allo-HSCT), who were randomly divided into two groups according to gender, type of transplantation, and type of primary disease. The control group was treated conventionally, and the experimental group increased moxibustion of Zhongji, Guanyuan and Qihai for 30 min qd starting on the first day after HSCT was performed until the 14th day after transplantation. Urine routine tests were performed at the time of admission, +1d, and +14d, and urine BK virus, JC virus, and adenovirus were tested at four time points, namely, +1d, +14 days, onset of hematuria symptoms, and remission of HC, respectively; routine urine tests were performed once every 7 days for all patients within 100days. For patients with Hemorrhagic cystitis (HC), daily severity grading, pain scoring, cystitis symptom scoring, use of antispasmodic and analgesic medications, and major TCM evidence were recorded with the aim of evaluating the efficacy of moxibustion in the prevention of HC in this patient population.

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