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Diagnostic and Monitoring Significance of ctDNA Methylation Analysis by NGS in Benign and Malignant Pulmonary Nodules

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研究单位: [1]AnchorDx Medical Co.,Ltd. [2]Department of Respiratory Medicine,The First People's Hospital of Yunnan Province Kunming,China [3]Department of Gerontal Respiratory Medicine,The Frist Hospital of Lanzhou University Lanzhou,China [4]Department of Respiration,The First Affiliated Hospital of Nanchang University Nanchang,China [5]Department of Pulmonary & Critical Care Medicine,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine Shanghai,China [6]Department of Pulmonary Medicine,Shanghai Chest Hospital,Shanghai Jiaotong University Shanghai,China [7]Department of Pulmonary Medicine,Zhongshan Hospital,Fudan University Shanghai,China [8]Department of Respiratory Medicine,Shanghai Pulmonary Hospital,Tongji University School of Medicine Shanghai,China [9]Department of Respiratory Medicine,Shantou Central Hospital Shantou,China

关键词: Circulating Tumor DNA (ctDNA) DNA Methylation Analysis Next-Generation Sequencing (NGS) Low-Dose Computed Tomography (LDCT)

研究目的:
AnchorDx is using circulating tumor DNA (ctDNA) methylation analysis by next-generation sequencing (NGS) to develop a blood-based assay for differentiating benign and malignant pulmonary nodules early. The purpose of this study is to evaluate the diagnostic performance of this assay in patients with pulmonary nodules.

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