Impact of preoperative sarcopenia on postoperative complications and survival outcomes of patients with esophageal cancer: a meta-analysis of cohort studies
机构：[1]Evidence-based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, China,[2]Evidence-based Medicine Center, School of BasicMedical Sciences, Lanzhou University, Lanzhou, China,[3]Department of Nursing, The First People’s Hospital of Yunnan Province, Kunming, China,行政职能机构护理部云南省第一人民医院[4]Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou, China[5]The Affiliated Hospital of Kunming University of Science and Technology, Kunming, China云南省第一人民医院
The effects of preoperative sarcopenia on postoperative complications and survival outcomes of patients undergoing esophageal cancer resection are controversial. From database establishment to 16 May 2021, we systematically searched PubMed, Embase, the Cochrane Library, Web of Science, and Chinese Biomedical Literature Database to collect relevant studies investigating the effects of preoperative sarcopenia on postoperative complications, survival outcomes, and the risk of a poor prognosis of patients undergoing esophagectomy. The Newcastle-Ottawa scale was used to evaluate the quality of the included literature, and RevMan 5.3 software was used for the meta-analysis. A total of 26 studies (3 prospective cohort studies and 23 retrospective cohort studies), involving 4,515 patients, were included. The meta-analysis showed that preoperative sarcopenia significantly increased the risk of overall complications (risk ratio [RR]: 1.15; 95% confidence interval [CI]: 1.08-1.22), pulmonary complications (RR: 1.78; 95% CI: 1.48-2.14), and anastomotic leakage (RR: 1.29; 95% CI: 1.04-1.59) and reduced the overall survival rate (hazard ratio: 1.12; 95% CI: 1.04-1.20) following esophageal cancer resection. Preoperative sarcopenia increased the risks of overall postoperative and pulmonary complications in patients undergoing esophageal cancer resection. For patients with esophageal cancer, assessing the preoperative risk of preoperative sarcopenia is necessary.
基金：
National Natural Science Foundation of China [81873184]
第一作者机构：[1]Evidence-based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, China,[2]Evidence-based Medicine Center, School of BasicMedical Sciences, Lanzhou University, Lanzhou, China,
共同第一作者：
通讯作者：
通讯机构：[1]Evidence-based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, China,[2]Evidence-based Medicine Center, School of BasicMedical Sciences, Lanzhou University, Lanzhou, China,[4]Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou, China[*1]No.199, Donggang West Road, Chengguan District, Lanzhou, Gansu 730000, China
推荐引用方式(GB/T 7714)：
Chen Fei,Chi Junting,Zhao Bing,et al.Impact of preoperative sarcopenia on postoperative complications and survival outcomes of patients with esophageal cancer: a meta-analysis of cohort studies[J].DISEASES OF THE ESOPHAGUS.2022,35(9):doi:10.1093/dote/doab100.
APA：
Chen, Fei,Chi, Junting,Zhao, Bing,Mei, Fan,Gao, Qianqian...&Ma, Bin.(2022).Impact of preoperative sarcopenia on postoperative complications and survival outcomes of patients with esophageal cancer: a meta-analysis of cohort studies.DISEASES OF THE ESOPHAGUS,35,(9)
MLA：
Chen, Fei,et al."Impact of preoperative sarcopenia on postoperative complications and survival outcomes of patients with esophageal cancer: a meta-analysis of cohort studies".DISEASES OF THE ESOPHAGUS 35..9(2022)
