机构：[1]Department of Cardiology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, 650032, China.昆明医科大学附属第一医院[2]Department of Endocrinology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, 650032, China.昆明医科大学附属第一医院
Aim & methods: Non-exosomal and exosomal ncRNAs have been reported to be involved in the regulation of coronary artery disease (CAD). Therefore, to explore the biological effects of non-exosomal/exosomal ncRNAs in CAD, the authors searched for studies published in the last 3 years on these ncRNAs in CAD and summarized their functions and mechanisms. Results: The authors summarized 120 non-exosomal ncRNAs capable of regulating CAD progression. In clinical studies, 47 non-exosomal and nine exosomal ncRNAs were able to serve as biomarkers for the diagnosis of CAD. Conclusion: Non-exosomal/exosomal ncRNAs are not only able to serve as biomarkers for CAD diagnosis but can also regulate CAD progression through ceRNA mechanisms and are a potential target for early clinical intervention in CAD.
第一作者机构：[1]Department of Cardiology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, 650032, China.
推荐引用方式(GB/T 7714)：
Li Jingru,Wu Xinyu,Ma Haocheng,et al.New developments in non-exosomal and exosomal ncRNAs in coronary artery disease[J].EPIGENOMICS.2022,14(21):1355-1372.doi:10.2217/epi-2022-0201.
APA：
Li Jingru,Wu Xinyu,Ma Haocheng,Sun Guihu,Ding Peng...&Wang Luqiao.(2022).New developments in non-exosomal and exosomal ncRNAs in coronary artery disease.EPIGENOMICS,14,(21)
MLA：
Li Jingru,et al."New developments in non-exosomal and exosomal ncRNAs in coronary artery disease".EPIGENOMICS 14..21(2022):1355-1372
