Purpose: The purpose of this study was to develop and evaluate a deep learning network for three-dimensional reconstruction of the spine from biplanar radiographs.Methods: The proposed approach focused on extracting similar features and multiscale features of bone tissue in biplanar radiographs. Bone tissue features were reconstructed for feature representation across dimensions to generate three-dimensional volumes. The number of feature mappings was gradually reduced in the recon-struction to transform the high-dimensional features into the three-dimensional image domain. We produced and made eight public datasets to train and test the proposed network. Two evaluation metrics were proposed and combined with four classical evaluation metrics to measure the performance of the method. Results: In comparative experiments, the reconstruction results of this method achieved a Hausdorff distance of 1.85 mm, a surface overlap of 0.2 mm, a volume overlap of 0.9664, and an offset distance of only 0.21 mm from the vertebral body centroid. The results of this study indicate that the proposed method is reliable.
基金：
National Natural Science Founda-tion of China [62063034]; Graduate Research Inno-vation Fund Project of Yunnan University
