详情页 - 云南省第一人民医院机构库

当前位置：首页 > 详情页

The features of male breast cancer in China: A real-world study

16| 认领 | 导出 | 链接全文 |

文献详情

资源类型：

WOS体系：

Pubmed体系：

收录情况： ◇ SCIE

作者：

机构： [a]Breast Disease Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China [b]Department of Breast and Thyroid Surgery, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, China [c]Department of Breast Surgery, Hebei Provincial Tumor Hospital, Shijiazhuang, China [d]Breast Cancer Institute, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Kunming, China [e]Department of Medical Oncology, Sun Yat-sen University Cancer Center, Guangzhou, China [f]Department of Breast Surgery, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China [g]Prevention and Cure Center of Breast Disease, The Third Hospital of Nanchang City, Nanchang, China [h]The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China [i]Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China [j]Department of Tumor Surgery, Fujian Provincial Hospital, Fuzhou, China [k]The Department of Breast Surgery, The First Hospital of China Medical University, Shenyang, China [l]Breast Center B Ward, The Affiliated Hospital of Qingdao University, Qingdao, China [m]Department of Breast Cancer, Cancer Center, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China [n]Department of Breast Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China [o]Department of Breast Surgery, The First People’s Hospital of Foshan, Foshan,China [p]Department of Thyroid and Breast Surgery, Peking University First Hospital, Beijing, China [q]Department of Breast Surgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, China [r]Department of Breast Disease, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China [s]Department of Breast, Jiangmen Central Hospital, Jiangmen, China [t]Department of Breast Disease, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China [u]Department of Breast Surgery, School of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou, China [v]Peking University Shenzhen Hospital, Shenzhen, China [w]Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin City, China [x]Department of Breast Surgery, Affiliated Sanming First Hospital of Fujian Medical University, Sanming, China [y]Jieyang People’s Hospital, Jieyang, China [z]Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China [aa]Diagnosis and Treatment Center of Breast Diseases, Shantou Central Hospital, Shantou, China [ab]The First Affiliated Hospital of Nanjing Medical University, Nanjing, China [ac]Department of Breast Oncology, Lianjiang Pepole’s Hospital, Lianjiang, China [ad]Guangdong Women and Children Hospital, Guangzhou, China [ae]Zhanjiang Central Hospital, Guangdong Medical University, Zhanjiang, China [af]Department of Breast Disease, Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine, Zhuhai City, China

出处：

DOI：

ISSN：

关键词： Male breast cancer China Characteristics Treatment Prognosis

摘要：

Male breast cancer (MBC) is a rare disease. Although several large-scale studies have investigated MBC patients in other countries, the features of MBC patients in China have not been fully explored. This study aims to explore the features of Chinese MBC patients comprehensively.We retrospectively collected data of MBC patients from 36 centers in China. Overall survival (OS) was evaluated by the Kaplan-Meier method, log-rank test, and Cox regression analyses. Multivariate Cox analyses were used to identify independent prognostic factors of the patients.In total, 1119 patients were included. The mean age at diagnosis was 60.9 years, and a significant extension over time was observed (P < 0.001). The majority of the patients (89.1 %) received mastectomy. Sentinel lymph node biopsy was performed in 7.8 % of the patients diagnosed in 2009 or earlier, and this percentage increased significantly to 38.8 % in 2020 or later (P < 0.001). The five-year OS rate for the population was 85.5 % [95 % confidence interval (CI), 82.8 %-88.4 %]. Multivariate Cox analysis identified taxane-based [T-based, hazard ratio (HR) = 0.32, 95 % CI, 0.13 to 0.78, P = 0.012] and anthracycline plus taxane-based (A + T-based, HR = 0.47, 95 % CI, 0.23 to 0.96, P = 0.037) regimens as independent protective factors for OS. However, the anthracycline-based regimen showed no significance in outcome (P = 0.175).As the most extensive MBC study in China, we described the characteristics, treatment and prognosis of Chinese MBC population comprehensively. T-based and A + T-based regimens were protective factors for OS in these patients. More research is required for this population.Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.

语种：

被引次数：

WOS：

PubmedID：

中科院(CAS)分区：

出版当年[2024]版：

无

最新[2023]版：

大类 | 2 区医学

小类 | 2 区妇产科学 3 区肿瘤学

JCR分区：

出版当年[2023]版：

Q1 OBSTETRICS & GYNECOLOGY Q1 ONCOLOGY

最新[2023]版：

Q1 OBSTETRICS & GYNECOLOGY Q1 ONCOLOGY

影响因子： 5.7 最新[2023版] 4.7 最新五年平均 5.7 出版当年[2023版] 4.7 出版当年五年平均 3.9 出版前一年[2022版]

第一作者：

第一作者机构： [a]Breast Disease Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

共同第一作者：

通讯作者：

推荐引用方式(GB/T 7714)：

APA：

MLA：

The features of male breast cancer in China: A real-world study

文献详情

相关文献