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Impact of gut microbiota on endometriosis: linking physical injury to mental health

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收录情况： ◇ SCIE

作者：

机构： [1]Department of Gynecology, The First People’s Hospital of Yunnan Province, Kunming, China, [2]The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China, [3]Yunnan Provincial Key Laboratory of Clinical Virology, Kunming, China, [4]Department of Information, The First People’s Hospital of Yunnan Province, Kunming, China

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关键词： endometriosis gut microbiota immune dysfunction estrobolome complement system

摘要：

Endometriosis is widely recognized as a chronic, inflammatory, and heterogeneous condition that can manifest in various anatomical locations within females. It is marked by estrogen-driven cycles of bleeding, cell proliferation, and fibrosis involving ectopic endometrial glands and stroma cells located outside the uterus. The limited understanding of its etiology and complex pathogenesis has created obstacles in achieving early diagnosis and developing effective treatments with minimal side effects. Consequently, endometriosis requires more in-depth research to unravel its pathogenesis. The gut microbiota, a key player in chronic diseases, significantly influences bodily metabolism and immune regulation. Emerging evidence links the gut microbiota to inflammation, estrogen metabolism, and immune responses-key factors in the onset and progression of endometriosis. This review examines the various mechanisms through which endometriosis and the gut microbiota interact, aiming to inspire new strategies for preventing and early treating endometriosis.Copyright © 2025 Yuanyue, Qian, Ling, Liufeng, Jing and Xiaomei.

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出版当年[2025]版：

无

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大类 | 2 区医学

小类 | 2 区免疫学 2 区微生物学

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出版当年[2024]版：

Q1 MICROBIOLOGY Q2 IMMUNOLOGY

最新[2024]版：

Q1 MICROBIOLOGY Q2 IMMUNOLOGY

影响因子： 4.8 最新[2024版] 5.5 最新五年平均 4.8 出版当年[2024版] 5.5 出版当年五年平均 4.6 出版前一年[2023版]

第一作者：

第一作者机构： [1]Department of Gynecology, The First People’s Hospital of Yunnan Province, Kunming, China, [2]The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China, [3]Yunnan Provincial Key Laboratory of Clinical Virology, Kunming, China,

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通讯作者：

通讯机构： [1]Department of Gynecology, The First People’s Hospital of Yunnan Province, Kunming, China, [2]The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China,

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