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The role of metabolic score for visceral fat in the prediction of atrial fibrillation recurrence risk after catheter ablation

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机构: [1]Kunming Univ Sci & Technol, Peoples Hosp Yunnan Prov 1, Affiliated Hosp, Div Cardiol,Yunnan Arrhythmia Res Ctr, Kunming, Peoples R China [2]Tianjin Med Univ, Sch Pharm, Dept Biopharmaceut, Tianjin, Peoples R China [3]Tianjin Med Univ, Sch Pharm, Tianjin Key Lab Technol Enabling Dev Clin Therapeu, Tianjin, Peoples R China
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关键词: metabolic score of visceral fat atrial fibrillation visceral obesity catheter ablation independent risk factor

摘要:
Background: Previous studies show that visceral fat tissue (VAT) play an important role in atrial fibrillation (AF). The metabolic score of visceral fat (METS-VF), a new surrogate to estimate VAT, is associated with cardiovascular mortality risk. In this study, we try to investigate the association between METS-VF and the risk of AF recurrence after catheter ablation. Methods: 478 consecutive patients underwent catheter ablation were obtained and used to assess the relationship between METS-VF and the risk of AF recurrence. Cox regression was used to calculate the hazard ration (HR) of METS-VF for the risk of AF recurrence. Restricted cubic splines (RCS) was used to assessed the linear relationship between METS-VF and the AF recurrence risk. Results: A total of 112(23.4%) patients experienced AF recurrence during 18.0 +/- 9.6 months follow-up. The AF recurrence rate was significantly higher in the highest quartile of METS-VF than the other three quartiles (log rank = 0.021). In the univariate cox regression, LAD, and MET-VF were associated with AF recurrence (p<0.0001). In the multiple Cox regression results, compared with the participants with lowest METS-VF (Q1), the hazard ratio (HR) (95% CI) for the AF recurrence risk was 1.29 (0.73, 2.29) for Q2 (p=0.39), 1.59 (0.88 - 2.87) for Q3 (p=0.12), and 2.22 (1.20, 4.12) for Q4 (p<0.01) respectively. Conclusions: METS-VF was positively associated with the elevated AF recurrence risk. Our findings show that the METS-VF could be used to AF recurrence risk stratification.

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大类 | 3 区 医学
小类 | 3 区 内分泌学与代谢
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出版当年[2024]版:
Q1 ENDOCRINOLOGY & METABOLISM
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Q1 ENDOCRINOLOGY & METABOLISM

影响因子: 最新[2024版] 最新五年平均 出版当年[2024版] 出版当年五年平均 出版前一年[2023版]

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第一作者机构: [1]Kunming Univ Sci & Technol, Peoples Hosp Yunnan Prov 1, Affiliated Hosp, Div Cardiol,Yunnan Arrhythmia Res Ctr, Kunming, Peoples R China
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通讯机构: [2]Tianjin Med Univ, Sch Pharm, Dept Biopharmaceut, Tianjin, Peoples R China [3]Tianjin Med Univ, Sch Pharm, Tianjin Key Lab Technol Enabling Dev Clin Therapeu, Tianjin, Peoples R China
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