Background: Previous studies show that visceral fat tissue (VAT) play an important role in atrial fibrillation (AF). The metabolic score of visceral fat (METS-VF), a new surrogate to estimate VAT, is associated with cardiovascular mortality risk. In this study, we try to investigate the association between METS-VF and the risk of AF recurrence after catheter ablation. Methods: 478 consecutive patients underwent catheter ablation were obtained and used to assess the relationship between METS-VF and the risk of AF recurrence. Cox regression was used to calculate the hazard ration (HR) of METS-VF for the risk of AF recurrence. Restricted cubic splines (RCS) was used to assessed the linear relationship between METS-VF and the AF recurrence risk. Results: A total of 112(23.4%) patients experienced AF recurrence during 18.0 +/- 9.6 months follow-up. The AF recurrence rate was significantly higher in the highest quartile of METS-VF than the other three quartiles (log rank = 0.021). In the univariate cox regression, LAD, and MET-VF were associated with AF recurrence (p<0.0001). In the multiple Cox regression results, compared with the participants with lowest METS-VF (Q1), the hazard ratio (HR) (95% CI) for the AF recurrence risk was 1.29 (0.73, 2.29) for Q2 (p=0.39), 1.59 (0.88 - 2.87) for Q3 (p=0.12), and 2.22 (1.20, 4.12) for Q4 (p<0.01) respectively. Conclusions: METS-VF was positively associated with the elevated AF recurrence risk. Our findings show that the METS-VF could be used to AF recurrence risk stratification.
基金:
Health Commission of Yunnan Province [2023-KHRCBZ-B18]; Yunnan Fundamental Research Projects [202401CF070012]
第一作者机构:[1]Kunming Univ Sci & Technol, Peoples Hosp Yunnan Prov 1, Affiliated Hosp, Div Cardiol,Yunnan Arrhythmia Res Ctr, Kunming, Peoples R China
共同第一作者:
通讯作者:
通讯机构:[2]Tianjin Med Univ, Sch Pharm, Dept Biopharmaceut, Tianjin, Peoples R China[3]Tianjin Med Univ, Sch Pharm, Tianjin Key Lab Technol Enabling Dev Clin Therapeu, Tianjin, Peoples R China
推荐引用方式(GB/T 7714):
Ma Yazhe,Gao Xiaolong,Sun Jianying,et al.The role of metabolic score for visceral fat in the prediction of atrial fibrillation recurrence risk after catheter ablation[J].FRONTIERS IN ENDOCRINOLOGY.2025,16:doi:10.3389/fendo.2025.1607497.
APA:
Ma, Yazhe,Gao, Xiaolong,Sun, Jianying,Kuang, Xiaohui,Zhang, Xi...&Fan, Jie.(2025).The role of metabolic score for visceral fat in the prediction of atrial fibrillation recurrence risk after catheter ablation.FRONTIERS IN ENDOCRINOLOGY,16,
MLA:
Ma, Yazhe,et al."The role of metabolic score for visceral fat in the prediction of atrial fibrillation recurrence risk after catheter ablation".FRONTIERS IN ENDOCRINOLOGY 16.(2025)