机构:[1]Department of Breast Thyroid Surgery, The First People’s Hospital of Yunnan Province, Kunming 650032, China外科片乳腺甲状腺外科云南省第一人民医院[2]Department of Geriatrics, The First Affiliated Hospital of Kunming Medical University, Kunming 650032, China昆明医科大学附属第一医院
Cervical lymph node metastasis occurs frequently in papillary thyroid carcinoma. We aim to analyze the predictive value of cervical lymph node metastasis ratio (LNR) in papillary thyroid carcinoma 5-year relapse-free survival in Asian. Databases (Web of Science, PubMed, EMBASE, OVID, Elsevier Science Direct, and ProQuest) were searched to get the related articles. General data, cut-off ratio of LNR, five years of disease-free survival ratio and relapse-free survival ratio at different LNR cut-off values were obtained directly from included literatures and analyzed by diagnostic meta-analysis. Deeks' funnel plot asymmetry analysis was done to identify the publication bias. A total of 3880 Asian papillary thyroid carcinoma (PTC) patients from 7 articles were included. The sensitivity, specialty, and Diagnostic Odds Ratio combined values of LNR were 0.77 [0.67, 0.85], 0.76 [0.62, 0.87], and 10.85 [5.41, 21.77] respectively. The AUROC value of LNR was 0.83 [0.80, 0.86]. Compared with the fixed probability (20%) in preliminary experiments, the positive likelihood ratio (PLR) increased to 45%, and the negative likelihood ratio (NLR) reduced to 7%. No publication bias was found by Deeks' test. In conclusion, LNR can be used as a moderate predictor in PTC 5-years relapse-free survival for Asian.
第一作者机构:[1]Department of Breast Thyroid Surgery, The First People’s Hospital of Yunnan Province, Kunming 650032, China
通讯作者:
通讯机构:[1]Department of Breast Thyroid Surgery, The First People’s Hospital of Yunnan Province, Kunming 650032, China[*1]Department of Breast Thyroid Surgery, The First People’s Hospital of Yunnan Province, 157 Jinbi Road, Kunming 650032, China
推荐引用方式(GB/T 7714):
Chen Jumin,Bai Junyun,Yang Kunxian.Prognostic value of cervical lymph node metastasis ratio in Asian papillary thyroid carcinoma 5-year relapse-free survival: a meta-analysis[J].INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE.2018,11(3):1401-1410.
APA:
Chen, Jumin,Bai, Junyun&Yang, Kunxian.(2018).Prognostic value of cervical lymph node metastasis ratio in Asian papillary thyroid carcinoma 5-year relapse-free survival: a meta-analysis.INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,11,(3)
MLA:
Chen, Jumin,et al."Prognostic value of cervical lymph node metastasis ratio in Asian papillary thyroid carcinoma 5-year relapse-free survival: a meta-analysis".INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 11..3(2018):1401-1410