机构：[1]Department of Medical, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, No 16, Jichang Road, Baiyun District, Guangzhou, Guangdong 510405, People's Republic of China深圳市中医院深圳医学信息中心[2]Bone and Soft Tissue Tumors Research Center of Yunnan Province, Department of Orthopaedics, The Third Affiliated Hospital of Kunming Medical University, Tumor Hospital of Yunnan Province, Kunming, Yunnan 650118, People's Republic of China
Osteosarcoma is the most common primary malignant bone tumor; its standard treatment includes neoadjuvant chemotherapy combined with surgery. Neoadjuvant chemotherapy has significantly improved the 5-year survival and limb salvage rates in osteosarcoma since the 1870s. The survival rate of patients with limb salvage was not inferior to that of amputees, and therefore, limb salvage has become the main surgical option for patients with osteosarcoma. The 5-year survival rate for osteosarcoma has plateaued. However, new advances in limb salvage therapy in osteosarcoma, including adjuvant chemotherapy, ablation techniques, bone transport techniques, and computer navigation techniques, are now available. This report summarizes the recent advances in limb salvage therapy for osteosarcoma over the past decade.
基金：
grants (no. 81372322 and
no. 81460440) from the National Natural Science Foundation of China,
a grant (no. 2014FB059) from the Joint Special Funds for the
Department of Science and Technology of Yunnan Province-Kunming
Medical University, grants (No. 2017NS196, 2017NS197) from the
Scientific Research Projects of Internal Research Institutions of Medical
and Health Units in Yunnan Province, and a grant (No. BSJJ201406)
from the Doctor Scientific Research Startup funds of Tumor Hospital of
Yunnan Province which the Third Affiliated Hospital of Kunming
Medical University.
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2018]版：
大类|4 区医学
小类|4 区肿瘤学
最新[2025]版：
大类|3 区医学
小类|3 区肿瘤学
第一作者：
第一作者机构：[1]Department of Medical, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, No 16, Jichang Road, Baiyun District, Guangzhou, Guangdong 510405, People's Republic of China[2]Bone and Soft Tissue Tumors Research Center of Yunnan Province, Department of Orthopaedics, The Third Affiliated Hospital of Kunming Medical University, Tumor Hospital of Yunnan Province, Kunming, Yunnan 650118, People's Republic of China
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Yang Yichun,Han Lei,He Zewei,et al.Advances in limb salvage treatment of osteosarcoma.[J].Journal of bone oncology.2018,10:36-40.doi:10.1016/j.jbo.2017.11.005.
APA：
Yang Yichun,Han Lei,He Zewei,Li Xiaojuan,Yang Suping...&Yang Zuozhang.(2018).Advances in limb salvage treatment of osteosarcoma..Journal of bone oncology,10,
MLA：
Yang Yichun,et al."Advances in limb salvage treatment of osteosarcoma.".Journal of bone oncology 10.(2018):36-40
