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Cellular Substrates for Cell-Based Tissue Engineering of Human Corneal Endothelial Cells

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机构: [1]Department of Ophthalmology, The Second People's Hospital of Yunnan Province (Fourth Affiliated Hospital of Kunming Medical University) Yunnan Eye Institute Key Laboratory of Yunnan Province for the Prevention and Treatment of ophthalmology (2017DG008) Provincial Innovation Team for Cataract and Ocular Fundus Disease (2017HC010) Expert Workstation of Yao Ke (2017IC064), Kunming 650021, China. [2]Department of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. [3]Tissue Tech, Inc., Ocular Surface Center, and Ocular Surface Research & Education Foundation, Miami, FL, 33173 USA. [4]Department of Ophthalmology, Yan' An Hospital of Kunming City, Kunming, 650051, China
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关键词: substrate tissue engineering endothelium collagen integrin focal adhesion kinase leukemia inhibitory factor

摘要:
Corneal endothelial tissue engineering aims to find solutions for blindness due to endothelial dysfunction. A suitable combination of endothelial cells, substrates and environmental cues should be deployed for engineering functional endothelial tissues. This manuscript reviews up-to-date topics of corneal endothelial tissue engineering with special emphasis on biomaterial substrates and their properties, efficacy, and mechanisms of supporting functional endothelial cells in vitro.

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出版当年[2019]版:
大类 | 3 区 医学
小类 | 3 区 医学:内科
最新[2023]版:
大类 | 3 区 医学
小类 | 3 区 医学:内科
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出版当年[2018]版:
Q2 MEDICINE, GENERAL & INTERNAL
最新[2023]版:
Q1 MEDICINE, GENERAL & INTERNAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2018版] 出版当年五年平均 出版前一年[2017版] 出版后一年[2019版]

第一作者:
第一作者机构: [1]Department of Ophthalmology, The Second People's Hospital of Yunnan Province (Fourth Affiliated Hospital of Kunming Medical University) Yunnan Eye Institute Key Laboratory of Yunnan Province for the Prevention and Treatment of ophthalmology (2017DG008) Provincial Innovation Team for Cataract and Ocular Fundus Disease (2017HC010) Expert Workstation of Yao Ke (2017IC064), Kunming 650021, China.
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通讯作者:
通讯机构: [1]Department of Ophthalmology, The Second People's Hospital of Yunnan Province (Fourth Affiliated Hospital of Kunming Medical University) Yunnan Eye Institute Key Laboratory of Yunnan Province for the Prevention and Treatment of ophthalmology (2017DG008) Provincial Innovation Team for Cataract and Ocular Fundus Disease (2017HC010) Expert Workstation of Yao Ke (2017IC064), Kunming 650021, China. [3]Tissue Tech, Inc., Ocular Surface Center, and Ocular Surface Research & Education Foundation, Miami, FL, 33173 USA. [*1]Department of Ophthalmology, Fourth Affiliated Hospital of Kunming Medical University, Second People's Hospital of Yunnan Province, Kunming 650021, China [*2]TissueTech, Inc., 7000 SW 97th Avenue, Suite 212, Miami, FL 33173, USA
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