机构:[1]Department of Ophthalmology, The Second People's Hospital of Yunnan Province (Fourth Affiliated Hospital of Kunming Medical University) Yunnan Eye Institute Key Laboratory of Yunnan Province for the Prevention and Treatment of ophthalmology (2017DG008) Provincial Innovation Team for Cataract and Ocular Fundus Disease (2017HC010) Expert Workstation of Yao Ke (2017IC064), Kunming 650021, China.[2]Department of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.江苏省人民医院[3]Tissue Tech, Inc., Ocular Surface Center, and Ocular Surface Research & Education Foundation, Miami, FL, 33173 USA.[4]Department of Ophthalmology, Yan' An Hospital of Kunming City, Kunming, 650051, China
Corneal endothelial tissue engineering aims to find solutions for blindness due to endothelial dysfunction. A suitable combination of endothelial cells, substrates and environmental cues should be deployed for engineering functional endothelial tissues. This manuscript reviews up-to-date topics of corneal endothelial tissue engineering with special emphasis on biomaterial substrates and their properties, efficacy, and mechanisms of supporting functional endothelial cells in vitro.
基金:
National Natural Science Foundation of China, (Grant Number
81560168, to Min Hu), and by the National Eye
Institute, National Institutes of Health, USA (Grant
Numbers R43 EY 02250201 and R44 EY 022502-02, to
Yingting Zhu).
第一作者机构:[1]Department of Ophthalmology, The Second People's Hospital of Yunnan Province (Fourth Affiliated Hospital of Kunming Medical University) Yunnan Eye Institute Key Laboratory of Yunnan Province for the Prevention and Treatment of ophthalmology (2017DG008) Provincial Innovation Team for Cataract and Ocular Fundus Disease (2017HC010) Expert Workstation of Yao Ke (2017IC064), Kunming 650021, China.
共同第一作者:
通讯作者:
通讯机构:[1]Department of Ophthalmology, The Second People's Hospital of Yunnan Province (Fourth Affiliated Hospital of Kunming Medical University) Yunnan Eye Institute Key Laboratory of Yunnan Province for the Prevention and Treatment of ophthalmology (2017DG008) Provincial Innovation Team for Cataract and Ocular Fundus Disease (2017HC010) Expert Workstation of Yao Ke (2017IC064), Kunming 650021, China.[3]Tissue Tech, Inc., Ocular Surface Center, and Ocular Surface Research & Education Foundation, Miami, FL, 33173 USA.[*1]Department of Ophthalmology, Fourth Affiliated Hospital of Kunming Medical University, Second People's Hospital of Yunnan Province, Kunming 650021, China[*2]TissueTech, Inc., 7000 SW 97th Avenue, Suite 212, Miami, FL 33173, USA
推荐引用方式(GB/T 7714):
Zhu Qin,Sun Hong,Yang Dongmei,et al.Cellular Substrates for Cell-Based Tissue Engineering of Human Corneal Endothelial Cells[J].INTERNATIONAL JOURNAL OF MEDICAL SCIENCES.2019,16(8):1072-1077.doi:10.7150/ijms.34440.
APA:
Zhu Qin,Sun Hong,Yang Dongmei,Tighe Sean,Liu Yongsong...&Hu Min.(2019).Cellular Substrates for Cell-Based Tissue Engineering of Human Corneal Endothelial Cells.INTERNATIONAL JOURNAL OF MEDICAL SCIENCES,16,(8)
MLA:
Zhu Qin,et al."Cellular Substrates for Cell-Based Tissue Engineering of Human Corneal Endothelial Cells".INTERNATIONAL JOURNAL OF MEDICAL SCIENCES 16..8(2019):1072-1077