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Trabecular meshwork cells are a valuable resource for cellular therapy of glaucoma

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收录情况： ◇ SCIE

作者：

机构： [1]Department of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China [2]Department of Ophthalmology, the Second People’s Hospital of Yunnan Province (Fourth Affiliated Hospital of Kunming Medical University), Yunnan Eye Institute, Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology (2017DG008), Provincial Innovation Team for Cataract and Ocular Fundus Disease, The Second People’s Hospital of Yunnan Province (2017HC010), Expert Workstation of Yao Ke (2017IC064), Kunming, China [3]Shenzhen University School of Medicine, Shenzhen Eye Hospital, Shenzhen, China [4]Tissue Tech, Inc., Ocular Surface Center, Ocular Surface Research & Education Foundation, Miami, Florida

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DOI：

关键词： glaucoma progenitor trabecular meshwork

摘要：

Trabecular meshwork (TM) contains a subset of adult stem cells or progenitors that can be differentiated into corneal endothelial cells, adipocytes and chondrocytes, but not osteocytes or keratocytes. Accordingly, these progenitors can be utilized as a cell-based therapy to prevent blindness caused by glaucoma, corneal endothelial dysfunction and other diseases in general. In this review, we review in vitro expansion techniques for TM progenitors, discuss their phenotypic properties, and highlight their potential clinical applications in various ophthalmic diseases.

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出版当年[2019]版：

大类 | 2 区医学

小类 | 2 区医学：研究与实验 3 区细胞生物学

最新[2023]版：

大类 | 2 区

医学

小类 | 2 区医学：研究与实验 3 区细胞生物学

JCR分区：

出版当年[2018]版：

Q1 MEDICINE, RESEARCH & EXPERIMENTAL Q2 CELL BIOLOGY

最新[2023]版：

Q2 CELL BIOLOGY Q2 MEDICINE, RESEARCH & EXPERIMENTAL

影响因子： 4.3 最新[2023版] 5.1 最新五年平均 4.658 出版当年[2018版] 4.408 出版当年五年平均 4.302 出版前一年[2017版] 4.486 出版后一年[2019版]

第一作者：

第一作者机构： [1]Department of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China

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通讯作者：

通讯机构： [4]Tissue Tech, Inc., Ocular Surface Center, Ocular Surface Research & Education Foundation, Miami, Florida [*1]Research and Development Department, TissueTech, Inc., Miami, FL

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