机构：[1]Yunnan Institute of Endemic Diseases Control and Prevention, Dali, P.R. China.[2]State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P.R. China.[3]The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, P.R. China.[4]Utrecht Centre for Tick-borne Diseases (UCTD), Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.[5]Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Pretoria, South Africa.[6]Chinese PLA General Hospital, Beijing, P.R. China.
Rare investigation on tick-borne pathogens was carried out in Yunnan, China. In this study, we did a survey on Ehrlichia infection in small mammals and ticks. A total of 40 small mammals and 49 ticks were collected from Tengchong, Yunnan province. PCR targeting 16S ribosomal RNA (rRNA), citrate synthase, GroEL heat-shock protein operon, and major outer membrane protein genes was performed and positive amplicons were sequenced.
The 40 small mammals were identified as 10 species, 2 (5.0%) of which were infected with Ehrlichia, 4 (10.0%) were infected with Anaplasma phagocytophilum and another 2 (5.0%) were infected with Candidatus Neoehrlichia mikurensis. Six (12.2%) ticks were positive for Ehrlichia and another two (4.1%) were infected with A. phagocytophilum. Neither small mammals nor ticks had coinfection. The detected Ehrlichia was named as Ehrlichia sp. YN04, which was in the same clade of Ehrlichia sp. 360 by phylogenetic analysis. The sequences of the pathogen recovered from small mammals and ticks were identical with each other.
The study reports one Ehrlichia species first detected from small mammals and ticks in mainland China. As Yunnan is a famous "Global Biodiversity Hotspot" in the world, we may expect much more tick-borne infectious pathogens existing and declare more public health attention in this region.
基金：
This study was financially supported by the State Key
Research Development Program of China (2016YFC
1200301, 2016YFC1201902, 2016YFC1202701), the Natural
Science Foundation of China (81621005, 81773492, and
81673235), and Technical Innovation Training Program of
Yunnan Province (2014HB0923).
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2018]版：
大类|4 区医学
小类|3 区公共卫生、环境卫生与职业卫生4 区传染病学
最新[2023]版：
大类|4 区医学
小类|4 区传染病学4 区公共卫生、环境卫生与职业卫生
第一作者：
第一作者机构：[1]Yunnan Institute of Endemic Diseases Control and Prevention, Dali, P.R. China.
通讯作者：
通讯机构：[2]State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P.R. China.[*1]State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and Epidemiology 20 Dong-Da Street, Fengtai District Beijing 100071 P.R. China
推荐引用方式(GB/T 7714)：
Du Chun-Hong,Liu Hong-Bo,Wei Ran,et al.Investigation on Ehrlichia Infection in Small Mammals and Ticks from Tengchong, Yunnan Province, Southern China.[J].Vector borne and zoonotic diseases (Larchmont, N.Y.).2018,18(10):563-566.doi:10.1089/vbz.2017.2205.
APA：
Du Chun-Hong,Liu Hong-Bo,Wei Ran,Jongejan Frans,Gao Zi-Hou...&Cao Wu-Chun.(2018).Investigation on Ehrlichia Infection in Small Mammals and Ticks from Tengchong, Yunnan Province, Southern China..Vector borne and zoonotic diseases (Larchmont, N.Y.),18,(10)
MLA：
Du Chun-Hong,et al."Investigation on Ehrlichia Infection in Small Mammals and Ticks from Tengchong, Yunnan Province, Southern China.".Vector borne and zoonotic diseases (Larchmont, N.Y.) 18..10(2018):563-566
