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The association of depressive symptoms with disability among adults in China.

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收录情况： ◇ SCIE ◇ SSCI

作者：
Peng Rui[a] * ; Wang Yongshi[a] ; Huang Yueqin[a] ; Liu Zhaorui[a] ; Xu Xiangdong[b] ; Ma Yanjuan[b] ; Wang Limin[c] ; Zhang Mei[c] ; Yan Yongping[d] ; Wang Bo[d] ; Xiao Shuiyuan[e] ; Zhou Liang[e] ; Li Lingjiang[f] ; Zhang Yan[f] ; Ma Chao[a] ; Zhang Tingting[a] ; Yan Jie[g] ; Ding Hua[g] ; Yu Yaqin[h] ; Kou Changgui[h] ; Xu Xiufeng[i] ; Lu Jin[i] ; Wang Zhizhong[j] ; He Shulan[j] ; Xu Yifeng[k] ; He Yanling[k] ; Li Tao[l] ; Guo Wanjun[l] ; Xu Guangming[m] ; Yin Huifang[m] ; Du Xiangdong[n] ; Wu Yue[o] ; Li Guohua[p] ; Jia Fujun[q] ; Shi Jianfei[r] ; Chen Zheli[s] ; Zhang Ning[t] ; Li Shengju[u] ;
机构： [a]Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing 100191, China [b]The Fourth People’s Hospital in Urumqi, Urumqi 830002, China [c]National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China [d]Department of Epidemiology, the Fourth Military Medical University, Xi’an 710032, Shaanxi Province, China [e]Department of Social Medicine and Health Management, School of Public Health, Central South University, Changsha 410078, Hunan, China [f]Mental Health Institute, the Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, China [g]Institute of Social Science Survey, Peking University, Beijing 100871, China [h]Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jilin, China [i]Department of Psychiatry, The First Affiliated Hospital of Kunming Medical University, Kunming 650032, Yunnan, China [j]Department of Epidemiology and Health Statistics, School of Public Health and Management, Ningxia Medical University, Yinchuan 750004, Ning Xia, China [k]Shanghai Mental Health Center, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, China [l]Mental Health Centre of West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China [m]Tianjin Anding Hospital, Tianjin 300222, China [n]Suzhou Guangji Hospital, Suzhou 215008, Jiangsu, China [o]The Affiliated Wuxi Mental Health Center with Nanjing Medical University, Wuxi, Jiangsu 214151, China [p]Chifeng Anding Hospital, Chifeng 024000, Inner Mongolia Autonomous Region, China [q]Guangdong General Hospital, Guangdong Mental Health Institute, Guangzhou 510120, Guangdong, China [r]Department of Psychiatry, Hangzhou Seventh People’s Hospital, Hangzhou 310013, Zhejiang, China s The Third People’ [s]Hospital of Huzhou, Huzhou 313000, Zhejiang, China [t]Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing 210029, Jiangsu, China [u]The Third People’s Hospital of Qinghai, Xining 810007, Qinghai, China
出处：
DOI： 10.1016/j.jad.2021.09.030
ISSN：

关键词： Major depressive disorder Depressive symptoms Disability Community survey

摘要：
The symptoms that patients with major depressive disorder (MDD) experience are the dominant contributing factors to its heavy disease burden. This study sought to identify key symptoms leading to disability in patients with MDD.Subjects consisted of patients who had a 12-month MDD diagnosis based on the China Mental Health Survey (CMHS). World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) was used to assess the degree of disability. The associations between depressive symptoms and disability were analyzed using a linear regression and logistic regression with a complex sampling design.Of the 32,552 community residents, 655 patients were diagnosed with 12-month MDD. The disability rate due to MDD was 1.06% (95% CI: 0.85%-1.28%) among adults in Chinese community and 50.7% (95% CI: 44.3%-57.1%) among MDD patients. Depression was associated with all functional losses measured by the WHODAS. Feelings of worthlessness in life or inappropriate guilt, and psychomotor agitation or retardation were the key symptoms related to disability. Economic status, co-morbidity of physical diseases or anxiety disorders were correlates of disability scores.The disability rate might be underestimated due to the exclusion of MDD patients living in hospitals. The effect of treatments on disability was excluded.Psychological symptoms, not somatic symptoms, contribute to disability in MDD patients. Disability worsens when physical diseases or anxiety disorders are present. More attention could be paid to psychological symptoms, physical diseases, and anxiety disorders in MDD patients with disabilities.Copyright © 2021. Published by Elsevier B.V.

基金：
National Key R&D Program of China (grant numbers 2017YFC0907800, 2017YFC0907801), the Special Research Project for Non-profit Public Service of the Chinese Ministry of Health (grant number 201202022) and the National Twelfth Five-Year Plan for Science and Technology Support of the Chinese Ministry of Science and Technology (grant numbers 2012BAI01B01 & 2015BAI13B00).
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2022]版：
大类 | 2 区 医学
小类 | 2 区 精神病学 2 区 临床神经病学
最新[2023]版：
大类 | 2 区 医学
小类 | 2 区 临床神经病学 2 区 精神病学
JCR分区：
出版当年[2021]版：
Q1 CLINICAL NEUROLOGY Q1 PSYCHIATRY
最新[2023]版：
Q1 CLINICAL NEUROLOGY Q1 PSYCHIATRY

影响因子： 最新[2023版] 最新五年平均 出版当年[2021版] 出版当年五年平均 出版前一年[2020版] 出版后一年[2022版]

第一作者：
第一作者机构： [a]Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing 100191, China
通讯作者：
推荐引用方式(GB/T 7714)：
Peng Rui,Wang Yongshi,Huang Yueqin,et al.The association of depressive symptoms with disability among adults in China.[J].JOURNAL OF AFFECTIVE DISORDERS.2022,296:189-197.doi:10.1016/j.jad.2021.09.030.
APA：
Peng Rui,Wang Yongshi,Huang Yueqin,Liu Zhaorui,Xu Xiangdong...&Li Shengju.(2022).The association of depressive symptoms with disability among adults in China..JOURNAL OF AFFECTIVE DISORDERS,296,
MLA：
Peng Rui,et al."The association of depressive symptoms with disability among adults in China.".JOURNAL OF AFFECTIVE DISORDERS 296.(2022):189-197

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