机构：[1]The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, People's Republic of China.[2]Ruili City Center for Disease Control and Prevention, Ruili, Yunnan, People's Republic of China.[3]University of Kunming Medical Science, Kunming, Yunnan, People's Republic of China.[4]Yunnan Provincial Center for Disease Control and Prevention, 158 Dongsi street, Kunming, Yunnan, 650022, People's Republic of China
Ruili is a border city in southwest China along the heroin trafficking route. In recent decades, the city has witnessed increased in HIV transmission. The current study aims to explore the spatiotemporal trends in HIV prevalence identify and map the spatial variation and clustering of factors associated with HIV transmission through drug use and heterosexual contact transmissions at the village level from 1989 through 2016.Geographic information system-based spatiotemporal analyses, including global and local spatial autocorrelation analyses and space-time scanning statistics, were applied to detect the location and extent of HIV/AIDS high-risk areas.Drug use and heterosexual contact were identified as the major transmission routes causing infection in Ruili. Results of global spatial analysis showed significant clustering throughout the city caused by transmission via drug use in the early phase of the epidemic and transmission via heterosexual contact in the late phase of the epidemic during the study period. Hotspots of transmission from drug use were randomly distributed throughout the city. However, the hotspots of transmission by heterosexual contact were located in the central area only around the Jiegao China-Myanmar land port. Space-time scanning showed that transmission from drug use clustered in the southwest area between 1989 and 1990, while transmission by heterosexual contact clustered in the central area between 2004 and 2014.Heterosexual contact has become the dominant mode of transmission. Interventions should focus on highly clustered area where is around the Jiegao land port.
基金：
funding of the epidemiology, early
warning and response techniques of major infectious diseases in the Belt
and Road Initiative (2018ZX10101002) when performing study design, data
collection, and interpretation of data, and funding of Guizhou construction
platform for talents training ([2017]5735–31) when performing data analysis
and manuscript writing.
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2019]版：
大类|3 区医学
小类|3 区传染病学
最新[2023]版：
大类|3 区医学
小类|3 区传染病学
第一作者：
第一作者机构：[1]The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, People's Republic of China.
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Jiang Li,Li Zhoulin,Huang Jin,et al.Spatiotemporal clusters of HIV/AIDS infections caused by drug use and heterosexual contact in Ruili city, China 1989-2016[J].BMC infectious diseases.2019,19(1):925.doi:10.1186/s12879-019-4568-0.
APA：
Jiang Li,Li Zhoulin,Huang Jin,Liu Bang,Yang Yingbo...&Li Hong.(2019).Spatiotemporal clusters of HIV/AIDS infections caused by drug use and heterosexual contact in Ruili city, China 1989-2016.BMC infectious diseases,19,(1)
MLA：
Jiang Li,et al."Spatiotemporal clusters of HIV/AIDS infections caused by drug use and heterosexual contact in Ruili city, China 1989-2016".BMC infectious diseases 19..1(2019):925
