详情页 - 云南省第一人民医院机构库

当前位置：首页 > 详情页

Extracellular vesicles: Targeting the heart

142| 导出 | 链接全文 |

文献详情

资源类型：

WOS体系：

Pubmed体系：

收录情况： ◇ SCIE

作者：

机构： [1]Faculty of Life Sciences and Technology, Kunming University of Science and Technology, Kunming, China. [2]Department of Ultrasound, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China. [3]The First People's Hospital of Yunnan, Kunming, Yunnan, China.

出处：

DOI：

ISSN：

关键词： extracellular vesicles cardiovascular diseases target delivery myocardial infarction exosome (vesicle)

摘要：

Cardiovascular diseases rank the highest incidence and mortality worldwide. As the most common type of cardiovascular disease, myocardial infarction causes high morbidity and mortality. Recent studies have revealed that extracellular vesicles, including exosomes, show great potential as a promising cell-free therapy for the treatment of myocardial infarction. However, low heart-targeting efficiency and short plasma half-life have hampered the clinical translation of extracellular vesicle therapy. Currently, four major types of strategies aiming at enhancing target efficiency have been developed, including modifying EV surface, suppressing non-target absorption, increasing the uptake efficiency of target cells, and utilizing a hydrogel patch. This presented review summarizes the current research aimed at EV heart targeting and discusses the challenges and opportunities in EV therapy, which will be beneficial for the development of effective heart-targeting strategies.Copyright © 2023 Yin and Jiang.

语种：

被引次数：

WOS：

PubmedID：

中科院(CAS)分区：

出版当年[2023]版：

大类 | 3 区医学

小类 | 3 区心脏和心血管系统

最新[2023]版：

大类 | 3 区医学

小类 | 3 区心脏和心血管系统

JCR分区：

出版当年[2022]版：

Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

最新[2023]版：

Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

影响因子： 2.8 最新[2023版] 3.1 最新五年平均 3.6 出版当年[2022版] 4.1 出版当年五年平均 5.848 出版前一年[2021版] 2.8 出版后一年[2023版]

第一作者：

第一作者机构： [1]Faculty of Life Sciences and Technology, Kunming University of Science and Technology, Kunming, China. [2]Department of Ultrasound, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China. [3]The First People's Hospital of Yunnan, Kunming, Yunnan, China.

通讯作者：

通讯机构： [2]Department of Ultrasound, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China. [3]The First People's Hospital of Yunnan, Kunming, Yunnan, China.

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]Injectable hydrogel with dual-sensitive behavior for targeted delivery of oncostatin M to improve cardiac restoration after myocardial infarction [2]Effect of Baseline Thrombocytopenia on Long-Term Outcomes in Patients With Acute ST-Segment Elevated Myocardial Infarction　- A Large Propensity Score-Matching Analysis From the China Acute Myocardial Infarction (CAMI) Registry. [3]Extracellular vesicles derived from PM2.5-exposed alveolar epithelial cells mediate endothelial adhesion and atherosclerosis in ApoE-/- mice [4]Small extracellular vesicles derived from acute myeloid leukemia cells promote leukemogenesis by transferring miR-221-3p [5]Global Burden of Cardiovascular Diseases and Risks, 1990-2022 [6]Applications, roles and problems of exosomes derived from different stem cells in the treatment of cardiovascular diseases [7]Predictive value of creatine kinase MB for contrast-induced acute kidney injury among myocardial infarction patients [8]Mesenchymal stem cell-derived extracellular vesicles prevent neural stem cell hypoxia injury via promoting miR-210-3p expression(Open Access) [9]Effects of Extracellular Vesicles Derived from Human Umbilical Cord Blood Mesenchymal Stem Cells on Cell Immunity in Nonobese Mice [10]Causal relationship between immune cells and risk of myocardial infarction: evidence from a Mendelian randomization study