机构：[1]Department of Pulmonary and Critical Care Medicine, The First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, China内科片外科片呼吸与危重症医学科重症医学科云南省第一人民医院[2]Department of Pulmonary and Critical Care Medicine, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China[3]College of Big Data and Internet, Shenzhen Technology University, Shenzhen, China[4]Wuerzburg Dynamics Inc., Shenzhen, China[5]Department of Interventional Radiology, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China
Background: As lung cancer is one of the most significant factors seriously endangering human health, a robot-assisted puncture system with high accuracy and safety is urgently needed. The purpose of this investigation was to compare the safety and effectiveness of such a robot-assisted system to the conventional computed tomography (CT)-guided manual method for percutaneous lung biopsies (PLBs) in pigs.Methods: An optical navigation robot-assisted puncture system was developed and compared to the traditional CT-guided PLB using simulated lesions in experimental animals. A total of 30 pulmonary nodules were successfully created in 5 pigs (Wuzhishan pig, 1 male and 4 females). Of these, 15 were punctured by the optical navigation robot-assisted puncture system (robotic group), and 15 were manually punctured under CT guidance (manual group). The biopsy success rate, operation time, first needle tip-target point deviation, and needle adjustment times were compared between groups. Postoperative CT scans were performed to identify complications.Results: The single puncture success rate was higher in the robotic group (13/15; 86.7%) than in the manual group (8/15; 53.3%). The first puncture was closer to the target lesion (1.8 +/- 1.7 mm), and the operation time was shorter (7.1 +/- 3.7 minutes) in the robotic group than in the manual group (4.4 +/- 2.8 mm and 12.9 +/- 7.6 minutes, respectively). The angle deviation was smaller in the robotic group (3.26(degrees) +/- 2.48(degrees)) than in the manual group (7.71(degrees) +/- 3.86(degrees)). The robotic group displayed significant advantages (P<0.05). The primary complication in both groups was slight bleeding, with an incidence of 26.7% in the robotic group and 40.0% in the manual group. There was 1 case of pneumothorax in the manual group, and there were no deaths due to complications in either group.Conclusions: An optical navigation robot-assisted system for PLBs guided by CT images was developed and demonstrated. The experimental results indicate that the proposed system is accurate, efficient, and safe in pigs.
基金：
Major Science and Technology Special Plan of Biological Medicine of Yunnan Province [0202002AA100075]; Project of the Educational Commission of Guangdong Province of China [2022ZDJS113]; School-Enterprise Cooperation Fund; Shenzhen Technology University
第一作者机构：[1]Department of Pulmonary and Critical Care Medicine, The First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, China[2]Department of Pulmonary and Critical Care Medicine, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China
共同第一作者：
通讯作者：
通讯机构：[2]Department of Pulmonary and Critical Care Medicine, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China[3]College of Big Data and Internet, Shenzhen Technology University, Shenzhen, China[*1]Department of Pulmonary and Critical Care Medicine, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, 106 Zhongshan 2nd Road, Guangzhou 510080, China[*2]College of Big Data and Internet, Shenzhen Technology University, 3002 Lantian Road, Shenzhen 518118, China.
推荐引用方式(GB/T 7714)：
Li Jing,Sun Liyilei,Liu Jun,et al.Optical navigation robot-assisted puncture system for accurate lung nodule biopsy: an animal study[J].QUANTITATIVE IMAGING IN MEDICINE AND SURGERY.2023,13(12):7789-7801.doi:10.21037/qims-23-576.
APA：
Li, Jing,Sun, Liyilei,Liu, Jun,Peng, Qian,Xu, Rongde...&Chen, Jingjing.(2023).Optical navigation robot-assisted puncture system for accurate lung nodule biopsy: an animal study.QUANTITATIVE IMAGING IN MEDICINE AND SURGERY,13,(12)
MLA：
Li, Jing,et al."Optical navigation robot-assisted puncture system for accurate lung nodule biopsy: an animal study".QUANTITATIVE IMAGING IN MEDICINE AND SURGERY 13..12(2023):7789-7801
