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Predictive value of intravascular ultrasound for the function of intermediate coronary lesions

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机构: [1]Department of Cardiology, Shanghai General Hospital of Nanjing Medical University, No.100, Haining Rd, Hongkou District, Shanghai 200080, China [2]Department of Cardiology, Shanghai General Hospital of Shanghai Jiao Tong University School of Medicine, No.100, Haining Rd, Hongkou District, Shanghai 200080, China [3]Department of Emergency, Shanghai General Hospital of Shanghai Jiao Tong University School of Medicine, No.100, Haining Rd, Hongkou District, Shanghai 200080, China [4]Menghai County People’s Hospital, Xishuangbanna, Yunnan Province, China [5]School of Oral Medicine, Nanjing Medical University, No.1, Shanghai RD, Nanjing City, Jiangsu Province, China
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关键词: Intravascular ultrasound (IVUS) Contrast-fow quantitative fow ratio (QFR) Logistic regression analysis ROC curve Intermediate coronary lesion

摘要:
Intravascular ultrasound (IVUS) can provide detailed coronary anatomic parameters. The purpose of our study was to evaluate the parameters measured by IVUS for the prediction of intermediate coronary lesions function by referencing quantitative fraction ratio (QFR) ≤ 0.80 (vs. > 0.80).Eighty four cases with 92 intermediate coronary lesions in vessels with a diameter ≥ 2.50 mm were enrolled. Paired assessment of IVUS and cQFR was available, and vessels with cQFR ≤ 0.8 were considered the positive reference standard. Logistic regression was used to select model variables by a maximum partial likelihood estimation test and receiver operating characteristic curve (ROC) analysis to evaluate the diagnostic value of different indices.Plaque burden (PB) and lesion length (LL) of IVUS were independent risk factors for the function of coronary lesions. The predictive probability P was derived from the combined PB and LL model. The area under the curve (AUC) of PB, (minimum lumen area) MLA, and LL and the predicted probability P are 0.789,0.732,0731, and 0.863, respectively (P < 0.01). The AUC of the predicted probability P was the biggest among them; the prediction accuracy of cQFR ≤ 0.8 was 84.8%, and the sensitivity of the diagnostic model was 0.826, specificity was 0. 725, and P < 0.01.PB and LL of IVUS were independent risk factors influencing the function of intermediate coronary lesions. The model combining the PB and LL may predict coronary artery function better than any other single parameter.© 2023. BioMed Central Ltd., part of Springer Nature.

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出版当年[2023]版:
大类 | 3 区 医学
小类 | 4 区 心脏和心血管系统
最新[2023]版:
大类 | 3 区 医学
小类 | 4 区 心脏和心血管系统
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第一作者机构: [1]Department of Cardiology, Shanghai General Hospital of Nanjing Medical University, No.100, Haining Rd, Hongkou District, Shanghai 200080, China
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