The effect of multi-component exercise intervention in older people with Parkinson's disease and mild cognitive impairment: A randomized controlled study
A multimodal exercise training program might be the best way to improve motor and cognitive function in patients with Parkinson's disease (PD), but this has yet to be fully proven in PD patients with mild cognitive impairment (MCI). This study aims to examine the feasibility and effectiveness of a theory-based, multi-component exercise intervention in older people with PD-MCI. Participants were randomized into an intervention group (n=23) and an active control group (n=23), receiving the theory-based multi-component exercise intervention and Parkinson's health exercises, respectively. All participants performed 60-minute exercise training sessions three times a week over a 12-week period. The retention rate at post-intervention was 95.7% (42/46) for the entire cohort. The attendance rates were 99.6% in the intervention group and 99.5% in the control group. No adverse events occurred. The intervention group showed significantly greater improvements than the control group in global cognitive function, executive function, physical motor function, balance and gait, depression, and quality of life. This study indicates that the theory-based multi-component exercise intervention demonstrates high feasibility in promoting exercise adherence and is an effective treatment option for older adults with PD-MCI.
基金:
Scientific Research of Fujian Medical University [2023J05224]; Fujian Natural Science Foundation of Fujian Province [2020Y9021]; Joint Funds for the Innovation of Science and Tech-nology of Fujian Province
第一作者机构:[1]Fuzhou Univ, Shengli Clin Med Coll, Fujian Med Univ, Fujian Prov Hosp,Affiliated Prov Hosp, Fuzhou, Peoples R China[2]Fujian Med Univ, Sch Nursing, 1 Xue Yuan Rd, Fuzhou, Fujian, Peoples R China
共同第一作者:
通讯作者:
通讯机构:[*1]The School of Nursing, Fujian Medical University, 1 Xue Yuan Road, University Town, Fuzhou, Fujian, China
推荐引用方式(GB/T 7714):
Yan Yuanjiao,Xu Yifei,Wang Xiaoxia,et al.The effect of multi-component exercise intervention in older people with Parkinson's disease and mild cognitive impairment: A randomized controlled study[J].GERIATRIC NURSING.2024,60:137-145.doi:10.1016/j.gerinurse.2024.08.028.
APA:
Yan, Yuanjiao,Xu, Yifei,Wang, Xiaoxia,Wang, Yunxian,Huang, Chenshan...&Li, Hong.(2024).The effect of multi-component exercise intervention in older people with Parkinson's disease and mild cognitive impairment: A randomized controlled study.GERIATRIC NURSING,60,
MLA:
Yan, Yuanjiao,et al."The effect of multi-component exercise intervention in older people with Parkinson's disease and mild cognitive impairment: A randomized controlled study".GERIATRIC NURSING 60.(2024):137-145