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Sex Differences in Primary and Secondary Prevention of Cardiovascular Disease in China

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收录情况： ◇ SCIE

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机构： [1]Beijing Anzhen Hospital, Capital Medical University, China [2]Heart Health Research Centre, Beijing, China [3]The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, Australia [4]Beijing Centre for Disease Prevention and Control, China [5]Cardiology Department,Royal Prince Alfred Hospital, Sydney, Australia [6]Neurology Department,Royal Prince Alfred Hospital, Sydney, Australia [7]Sydney Medical School, University of Sydney, Australia [8]National Heart Centre Singapore and Duke-National University of Singapore [9]University Medical Centre Groningen, The Netherlands [10]Northwestern University Feinberg School of Medicine, Chicago, IL [11]Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University, Japan [12]The Seventh People’s Hospital of Zhengzhou, Henan Province, China [13]Department of Cardiology, The First Hospital of Jilin University, Changchun, China [14]Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China [15]Department of Cardiology, Yanan Hospital of Kunming, Kunming, Yunnan Province, China [16]Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumchi, Xinjiang Uyghur Autonomous Region, China [17]Yinzhou District Centre for Disease Control and Prevention, Ningbo, Zhejiang Province, China [18]Cardiovascular Department, The Second Affiliated Hospital of Nanchang University, Jiangxi Province, China [19]The George Institute China at Peking University Health Science Centre, China [20]The First Affiliated Hospital of Zhengzhou University, Henan Province, China

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关键词： Cardiovascular diseases China Health Primary prevention Secondary prevention Sex characteristics

摘要：

Background: Despite improvements in diagnostic and therapeutic interventions to combat cardiovascular disease (CVD) in recent decades, there are significant ongoing access gaps and sex disparities in prevention that have not been adequately quantified in China. Methods: A representative, cross-sectional, community-based survey of adults (aged ≥45 years) was conducted in 7 geographic regions of China between 2014 and 2016. Logistic regression models were used to determine sex differences in primary and secondary CVD prevention, and any interaction by age, education level, and area of residence. Data are presented as adjusted odds ratios (ORs) and 95% CIs. Results: Of 47 841 participants (61.3% women), 5454 (57.2% women) had established CVD and 9532 (70.5% women) had a high estimated 10-year CVD risk (≥10%). Only 48.5% and 48.6% of women and 39.3% and 59.8% of men were on any kind of blood pressure (BP)-lowering medication, lipid-lowering medication, or antiplatelet therapy for primary and secondary prevention, respectively. Women with established CVD were significantly less likely than men to receive BP-lowering medications (OR, 0.79 [95% CI, 0.65-0.95]), lipid-lowering medications (OR, 0.69 [95% CI, 0.56-0.84]), antiplatelets (OR, 0.53 [95% CI, 0.45-0.62]), or any CVD prevention medication (OR, 0.62 [95% CI, 0.52-0.73]). Women with established CVD, however, had better BP control (OR, 1.31 [95% CI, 1.14-1.50]) but less well-controlled low-density lipoprotein cholesterol (OR, 0.66 [95% CI, 0.57-0.76]), and were less likely to smoke (OR, 13.89 [95% CI, 11.24-17.15]) and achieve physical activity targets (OR, 1.92 [95% CI, 1.61-2.29]). Conversely, women with high CVD risk were less likely than men to have their BP, low-density lipoprotein cholesterol, and bodyweight controlled (OR, 0.46 [95% CI, 0.38-0.55]; OR, 0.60 [95% CI, 0.52-0.69]; OR, 0.55 [95% CI, 0.48-0.63], respectively), despite a higher use of BP-lowering medications (OR, 1.21 [95% CI, 1.01-1.45]). Younger patients (<65 years) with established CVD were less likely to be taking CVD preventive medications, but there were no sex differences by area of residence or education level. Conclusions: Large and variable gaps in primary and secondary CVD prevention exist in China, particularly for women. Effective CVD prevention requires an improved overall nationwide strategy and a special emphasis on women with established CVD, who have the greatest disparity and the most to benefit. © 2019 by the American Society of Plastic Surgeons.

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出版当年[2020]版：

大类 | 1 区

医学

小类 | 1 区心脏和心血管系统 1 区外周血管病

最新[2023]版：

大类 | 1 区

医学

小类 | 1 区心脏和心血管系统 1 区外周血管病

JCR分区：

出版当年[2019]版：

Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Q1 PERIPHERAL VASCULAR DISEASE

最新[2023]版：

Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Q1 PERIPHERAL VASCULAR DISEASE

影响因子： 35.6 最新[2023版] 32.8 最新五年平均 23.603 出版当年[2019版] 21.054 出版当年五年平均 23.054 出版前一年[2018版] 29.69 出版后一年[2020版]

第一作者：

第一作者机构： [1]Beijing Anzhen Hospital, Capital Medical University, China

通讯作者：

通讯机构： [1]Beijing Anzhen Hospital, Capital Medical University, China [2]Heart Health Research Centre, Beijing, China [3]The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, Australia [*1]Beijing Anzhen Hospital, Capital Medical University, No. 2 Anzhen Rd, Chaoyang District, Beijing 100029, China [*2]Beijing Anzhen Hospital, Capital Medical University, No. 2 Anzhen Rd, Chaoyang District, Beijing 100029, China

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Sex Differences in Primary and Secondary Prevention of Cardiovascular Disease in China

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