机构:[1]Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming 650031, PR China[2]Research and Development Center, China Tobacco Yunnan Industrial Co., Ltd., Kunming 650231, PR China[3]Clinical Laboratory, First People’s Hospital of Yunnan Province, Kunming 650032, PR China医技片检验科云南省第一人民医院
Three new arylbenzofurans, 7-methoxy-2-(4-methoxyphenyl)-3-methyl-5-(3-prenyl)-benzofuran (1), 2(4-methoxyphenyl)-3-methyl-5-(3-prenyl)-benzofuran-7-ol (2), 2-(4-hydroxy-3,5-dimethoxyphenyl)3- methyl-5-(3-prenyl) benzofuran-7-ol (3), along with four known arylbenzofurans (4-7) were isolated from the fermentation products of an endophytic Phomopsis sp. Their structures were elucidated by spectroscopic methods including extensive 1D-and 2D-NMR techniques. In addition, compounds 1-7 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compound 3 exhibited obvious anti-TMV activity with inhibition rate of 35.2% better than that of positive control (31.8%). The other compounds also showed potential anti-TMV activity with inhibition rates in the range of 18.6-25.7%, respectively. (C) 2016 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.
基金:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [21462051, 31560099]; Scientific Research Fund Key Project of Education Department of Yunnan Province [2013Z038]; program for Innovative Research Team (in Science and Technology) in University of Yunnan Provinve [IRTSTYN 2014-11]
第一作者机构:[1]Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming 650031, PR China
通讯作者:
推荐引用方式(GB/T 7714):
Du Gang,Wang Zhong-Cheng,Hu Wei-Yao,et al.Three new 3-methyl-2-arylbenzofurans from the fermentation products of an endophytic fungus Phomopsis sp and their anti-TMV activity[J].PHYTOCHEMISTRY LETTERS.2017,21:287-290.doi:10.1016/j.phytol.2016.04.003.
APA:
Du, Gang,Wang, Zhong-Cheng,Hu, Wei-Yao,Yan, Ke-Liang,Wang, Xin-Lin...&Hu, Qiu-Fen.(2017).Three new 3-methyl-2-arylbenzofurans from the fermentation products of an endophytic fungus Phomopsis sp and their anti-TMV activity.PHYTOCHEMISTRY LETTERS,21,
MLA:
Du, Gang,et al."Three new 3-methyl-2-arylbenzofurans from the fermentation products of an endophytic fungus Phomopsis sp and their anti-TMV activity".PHYTOCHEMISTRY LETTERS 21.(2017):287-290