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The prevalence and genotype distribution of rotavirus A infection among children with acute gastroenteritis in Kunming, China

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机构: [1]Faculty of Environmental Science and Engineering, Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming 650500, Yunnan, China [2]Department of Clinical Laboratory, First People’s Hospital of Yunnan Province, Kunming 650032, Yunnan, China [3]Department of Clinical Laboratory, Kunming Children’s Hospital, Kunming 650034, Yunnan, China [4]Department of Information Center, First People’s Hospital of Yunnan province, Kunming 650032, Yunnan, China
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关键词: Rotavirus A Children Gastroenteritis Epidemiology Genotype

摘要:
The aim of this study was to determine the prevalence of rotavirus A (RVA) infections in children from Kunming, China, and the RVA genotypes present. A total of 16,311 children with acute gastroenteritis were recruited for the study, and 33.1 % (5,394/16,311) were RVA positive. Children under 24 months of age were more susceptible to RVA infection, with an infection rate of 87.4 % (4,712/5,394). The most prevalent genotype was G9P[8] (85/107, 79.4 %), which showed high sequence similarity to G9P[8] strains from other regions of China and neighbouring countries, but not to the licensed vaccine strain LLR. These findings should be useful for the prevention of RVA infections.

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出版当年[2017]版:
大类 | 3 区 医学
小类 | 4 区 病毒学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 病毒学
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出版当年[2016]版:
Q3 VIROLOGY
最新[2023]版:
Q3 VIROLOGY

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第一作者机构: [1]Faculty of Environmental Science and Engineering, Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming 650500, Yunnan, China [2]Department of Clinical Laboratory, First People’s Hospital of Yunnan Province, Kunming 650032, Yunnan, China
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