机构：[1]National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, People’s Republic of China[2]Key Laboratory for Parasitology and Vector Biology, MOH of China, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai, People’s Republic of China[3]Yunnan Provincial Center for Disease Control and Prevention, Kunming, People’s Republic of China[4]The first people’s Hospital of Yunnan province, Kunming, People’s Republic of China云南省第一人民医院[5]National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China
Group A rotavirus (RVA) is one of the leading cause of acute diarrhea worldwide, the RVA-related disease burden and the genotypes of RVA is important reference to introduce RVA variance to national immunisation programmes, 1,121 diarrhea cases and 319 healthy controls were recruited from four sentinel hospital outpatient from July 2014 to June 2015. The prevalence of RVA was 244 (21.8%) in gastroenteritis cases and in 12 (3.8%) in healthy controls across all age group (OR=7.12, 95%CI=3.93-12.89); the detection rate of RVA in diarrhea patients under 5 years was more higher than in diarrhea cases over 5 years (26.1%, 222/850; 8.1%, 22/271, respectively, P=0.000). Of 244 RVA strains isolated from acute diarrhea cases, G9 (66.4%) was predominant G genotype, followed by G3 (18.7%), G1 (8.9%), and G1G3 (3.8%); P[8] was the overwhelming prevalence P genotype, followed by P[4] (4.7%); G9P[8] (54.9%) was most common G and P Combination, followed by G3P[8] (17.6%) and G1[8] (8.6%). The conclusion of the study was important to provide reference for introducing the RVA vaccine to prevent and control RVA-associated disease burden. J. Med. Virol. 89:71-78, 2017. (c) 2016 Wiley Periodicals, Inc.
基金：
National Science and Technology Major
Project; Grant numbers: 2008ZX10004-011; 2012ZX10004-220;
Grant sponsor: National Natural Science Foundation of China;
Grant number: 81473022
第一作者机构：[1]National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, People’s Republic of China[2]Key Laboratory for Parasitology and Vector Biology, MOH of China, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai, People’s Republic of China
通讯作者：
通讯机构：[1]National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, People’s Republic of China[2]Key Laboratory for Parasitology and Vector Biology, MOH of China, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai, People’s Republic of China[3]Yunnan Provincial Center for Disease Control and Prevention, Kunming, People’s Republic of China[*1]Yunnan Provincial Center for Disease Control and Prevention, Kunming 650022, People’s Republic of China.[*2]National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, and Key Laboratory for Parasitology and Vector Biology, MOH of China, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 20025, People’s Republic of China.
推荐引用方式(GB/T 7714)：
Zhang Shunxian,Yin Jianwen,Yang Jinhui,et al.Epidemiology and genetic diversity of group A rotavirus in acute diarrhea patients in pre-vaccination era in southwest China[J].JOURNAL OF MEDICAL VIROLOGY.2017,89(1):71-78.doi:10.1002/jmv.24606.
APA：
Zhang, Shunxian,Yin, Jianwen,Yang, Jinhui,Tian, Liguang,Li, Dandi...&Zhou, Xiaonong.(2017).Epidemiology and genetic diversity of group A rotavirus in acute diarrhea patients in pre-vaccination era in southwest China.JOURNAL OF MEDICAL VIROLOGY,89,(1)
MLA：
Zhang, Shunxian,et al."Epidemiology and genetic diversity of group A rotavirus in acute diarrhea patients in pre-vaccination era in southwest China".JOURNAL OF MEDICAL VIROLOGY 89..1(2017):71-78
