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Synthesis and Antitumor Activities of Two Novel Naphthol Derivatives

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收录情况： ◇ SCIE

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机构： [1]First Peoples Hosp Yunnan Prov,Dept Urol,Kunming,Yunnan,Peoples R China [2]First Peoples Hosp Yunnan Prov,Dept Emergency Traumatol,Kunming,Yunnan,Peoples R China [3]First Peoples Hosp Yunnan Prov,Dept Radiol,Kunming,Yunnan,Peoples R China

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关键词： antitumor crystal naphthol

摘要：

Two novel naphthol derivatives (1 and 2) were synthesized and characterized via IR, 1H NMR, HRMS, and single crystal X-ray crystallography. The antitumor activities of the two compounds were investigated against mouse leukemia L1210 cells, human oral epidermoid carcinoma KB cells, human promyelocytic leukemia cells (HL-60) and Bel-7402 liver cancer cells by MTT assay. It was found that compared with compound 1, compound 2 exerted rather potent activity against all of these cell lines.

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出版当年[2016]版：

大类 | 4 区医学

小类 | 4 区药学

最新[2023]版：

大类 | 4 区医学

小类 | 4 区药学

JCR分区：

出版当年[2015]版：

Q4 PHARMACOLOGY & PHARMACY

最新[2023]版：

无

影响因子： 0 最新[2023版] 0 最新五年平均 0.329 出版当年[2015版] 0.298 出版当年五年平均 0.372 出版前一年[2014版] 0.298 出版后一年[2016版]

第一作者：

第一作者机构： [1]First Peoples Hosp Yunnan Prov,Dept Urol,Kunming,Yunnan,Peoples R China

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