机构:[1]Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Peoples R China[2]Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Peoples R China[3]Chinese Acad Sci, Grad Sch, Beijing, Peoples R China[4]First Peoples Hosp Yunnan Prov, Kunming, Peoples R China云南省第一人民医院[5]Chinese Univ Hong Kong, Sch Biomed Sci, Hong Kong, Hong Kong, Peoples R China[6]Kunming Med Coll, Affiliated Hosp 2, Kunming, Peoples R China
Syncytin is a placenta-specific protein and generally believed to play a pivotal role in syncytiotrophoblast morphogenesis. In this study, transcripts of this gene were quantified by real-time RT-PCR and the translated products were measured by an indirect immunofluorescence assay. Results showed that syncytin was found to be expressed in all nine leukemia and lymphoma cell lines studied albeit at different levels and in 43 peripheral blood samples of 57 leukemia or lymphoma patients. Neither the transcripts nor the translated syncytin was detected in blood samples of normal individuals. In conclusion, peripheral blood syncytin may serve as a marker for leukemia and lymphoma. (C) 2010 Elsevier Ltd. All rights reserved.
基金:
Western Light of CAS to Y. Sun and the China postdoctoral Science Foundation
(20090451433) to W. Pang
第一作者机构:[1]Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Peoples R China[2]Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Peoples R China[3]Chinese Acad Sci, Grad Sch, Beijing, Peoples R China[4]First Peoples Hosp Yunnan Prov, Kunming, Peoples R China
通讯作者:
通讯机构:[1]Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Peoples R China[2]Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Peoples R China
推荐引用方式(GB/T 7714):
Sun Yi,Ouyang Dong-Yun,Pang Wei,et al.Expression of syncytin in leukemia and lymphoma cells[J].LEUKEMIA RESEARCH.2010,34(9):1195-1202.doi:10.1016/j.leukres.2010.03.016.
APA:
Sun, Yi,Ouyang, Dong-Yun,Pang, Wei,Tu, Yuan-Quan,Li, Yu-Ye...&Zheng, Yong-Tang.(2010).Expression of syncytin in leukemia and lymphoma cells.LEUKEMIA RESEARCH,34,(9)
MLA:
Sun, Yi,et al."Expression of syncytin in leukemia and lymphoma cells".LEUKEMIA RESEARCH 34..9(2010):1195-1202