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Malakoplakia of the esophagus caused by human papillomavirus infection

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机构: [1]Department of Pathology, Yunnan Province Second People’s Hospital, Kunming 650021, Yunnan Province, China Xiao-Ling Li, Department of Pathology, Changzhou Traditional Chinese Medical Hospital, Changzhou 231000, Jiangsu Province, China
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关键词: Malakoplakia Esophagus Michaelis-Gutmann bodies Human papillomavirus infection

摘要:
Malakoplakia is a rare granulomatous disease probably caused by infection and characterized histologically by Michaelis-Gutmann bodies. We report a more rarely seen case esophageal malakoplakia in a 54-year-old woman. She presented with coughing while eating and drinking. Gastroscopy showed yellow nodules in the esophagus, and endoscopic ultrasonography showed a space-occupying lesion in the substratum of the esophageal mucosa. All findings highly resembled esophageal cancer. Histopathological examination finally indentified this space-occupying lesion as malakoplakia and not cancer. Immunohistochemistry showed that she had human papillomavirus (HPV) infection in the esophagus, which indicates that infection was responsible for the malakoplakia. This is believed to be the first case of malakoplakia in the esophagus, and more importantly, we established that HPV infection was the initiator of esophageal malakoplakia.

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出版当年[2012]版:
大类 | 3 区 医学
小类 | 4 区 胃肠肝病学
最新[2023]版:
大类 | 3 区 医学
小类 | 3 区 胃肠肝病学
第一作者:
第一作者机构: [1]Department of Pathology, Yunnan Province Second People’s Hospital, Kunming 650021, Yunnan Province, China Xiao-Ling Li, Department of Pathology, Changzhou Traditional Chinese Medical Hospital, Changzhou 231000, Jiangsu Province, China [*1]Department of Pathology, Yunnan Province Second People’s Hospital, Kunming 650021, Yunnan Province, China
通讯作者:
通讯机构: [1]Department of Pathology, Yunnan Province Second People’s Hospital, Kunming 650021, Yunnan Province, China Xiao-Ling Li, Department of Pathology, Changzhou Traditional Chinese Medical Hospital, Changzhou 231000, Jiangsu Province, China [*1]Department of Pathology, Yunnan Province Second People’s Hospital, Kunming 650021, Yunnan Province, China
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